Maximal Respiratory Mouth Pressures Assessment in Stable Chronic Obstructive Pulmonary Disease Patients in a Tertiary Hospital in Southwest Nigeria

Authors

  • Oluwafunmilayo Oguntoye Department of Medicine, Faculty of Clinical Science, Afe Babalola University Ado Ekiti, Ekiti State, 360001, Nigeria. and Department of Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, 371101, Nigeria.
  • Gregory Erhabor Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, 220007, Nigeria.
  • Olufemi Adewole Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, 220007, Nigeria.
  • Olayemi Awopeju Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, 220007, Nigeria.
  • Bolanle Adefuye Department of Medicine, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, 121101, Nigeria.
  • Eruke Egbagbe Department of Medicine, University of Benin Teaching Hospital, Benin City, Edo State, 300001, Nigeria.
  • Temitope Kolawole Department of Medicine, Faculty of Clinical Science, Afe Babalola University Ado Ekiti, Ekiti State, 360001, Nigeria. and Department of Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, 371101, Nigeria.
  • Oluwatosin Oguntoye Department of Medicine, Faculty of Clinical Science, Afe Babalola University Ado Ekiti, Ekiti State, 360001, Nigeria. and Department of Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, 371101, Nigeria.
  • Abidemi Fasae Department of Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, 371101, Nigeria.
  • Paul Olowoyo Department of Medicine, Faculty of Clinical Science, Afe Babalola University Ado Ekiti, Ekiti State, 360001, Nigeria. and Department of Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, 371101, Nigeria.
  • Azeez Ibrahim Department of Medicine, Faculty of Clinical Science, Afe Babalola University Ado Ekiti, Ekiti State, 360001, Nigeria. and Department of Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, 371101, Nigeria.
  • Adenike Arawomo Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, 220007, Nigeria.
  • Oluwatosin Jegede United Nations Office on Drugs and Crime, Abuja, Federal Capital Territory, 900001, Nigeria.
  • Olumuyiwa Ariyo Department of Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, 371101, Nigeria.

DOI:

https://doi.org/10.31584/jhsmr.2023993

Keywords:

COPD, maximal respiratory mouth pressure, PEmax, Plmax, respiratory muscle strength

Abstract

Objective: This study aimed to assess the respiratory muscle strength in stable chronic obstructive pulmonary disease (COPD) patients, via measuring maximal respiratory mouth pressures [maximal inspiratory pressure (PImax) and maximal expiratory pressure (PEmax)] to determine its association with disease severity and quality of life.
Material and Methods: The study was a cross-sectional comparative study. A hundred and forty subjects (70 COPD patients and 70 controls) were recruited. Measurements of PImax, PEmax and spirometry were then performed. The health-related quality of life, severity of obstruction and dyspnea in the COPD patients were assessed using the COPD Assessment Test (CAT), post-bronchodilator Forced Expiratory Volume in 1 second (FEV 1) and the modified Medical Research Council (mMRC) dyspnea scale, respectively. Data was analyzed using Statistical Package for the Social Science (SPSS) version 25.0 (SPSS IL USA.).
Results: The mean (±S.D.) PImax and PEmax of the COPD patients (31.78±14.40 cmH2O and 54.80±18.89 cmH2O, respectively) were significantly lower (p<0.001) than the controls (80.40±7.50 cmH2O and 95.44±12.52 cmH2O, respectively). Both the PImax and PEmax correlated positively with the FEV1 of the COPD patients (r=0.658 and 0.534, respectively, p<0.001). The PImax and PEmax decreased as the mMRC dyspnea grade worsened (p<0.001). There was a negative correlation between PImax; PEmax and the CAT score of the COPD patients (r=-0.704 and–0.583, respectively, p<0.001).
Conclusion: There was significant respiratory muscle weakness in the COPD patients compared with the controls. The respiratory muscle weakness worsened as the airflow obstruction and dyspnea worsened. Respiratory muscle weakness may also add to the negative impact COPD has on the health status of COPD patients.

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Published

2024-01-31

How to Cite

1.
Oguntoye O, Erhabor G, Adewole O, Awopeju O, Adefuye B, Egbagbe E, Kolawole T, Oguntoye O, Fasae A, Olowoyo P, Ibrahim A, Arawomo A, Jegede O, Ariyo O. Maximal Respiratory Mouth Pressures Assessment in Stable Chronic Obstructive Pulmonary Disease Patients in a Tertiary Hospital in Southwest Nigeria. J Health Sci Med Res [Internet]. 2024 Jan. 31 [cited 2024 Dec. 23];42(2):e2023993. Available from: https://he01.tci-thaijo.org/index.php/jhsmr/article/view/268633

Issue

Vol. 42 No. 2 (2024): Mar-Apr

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Original Article

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