Multiple Cranial Neuropathies Caused by Lymphoma-Associated Central Nervous System Involvement in an Immunodeficiency Virus Patient
DOI:
https://doi.org/10.31584/jhsmr.202079Keywords:
cranial neuropathies, HIV, lymphomaAbstract
Human immunodeficiency virus (HIV) infections increase the risk of malignant lymphoma. Although, lymphoma is a rare cause of central nervous system involvement, it can present as an initial HIV symptom. We report the case of a 35-year-old HIV patient who developed multiple cranial neuropathies. He was diagnosed with diffuse large B-cell lymphoma with meningeal metastasis.
References
Grogg KL, Miller RF, Dogan A. HIV infection and lymphoma. J Clin Pathol 2007;60:1365-72.
Bomgaars L, Chamberlain MC, Poplack DG, Blaney S. Lepto meningeal metastases. In: Levin VA, editor. Cancer in the nervous system. 2nd ed. New York: Oxford University Press; 2002;p.375–93.
Powles T, Matthews G, Bower M. AIDS related systemic non Hodgkin's lymphoma. Sex Transm Infect 2000;76:335-41.
Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 2016;127:2375-90.
Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. Incidence of cancers in people with HIV/AIDS compared with immuno suppressed transplant recipients: a meta-analysis. Lancet 2007;370:59-67.
Gloghini A, Carbone A, Pantanowitz L. HIV-associated lymphomas. Atlas Genet Cytogenet Oncol Haematol 2017;21:25-9.
Sukpanichnant S, Sonakul D, Piankijagum A, Wanachiwanawin W, Veerakul G, Mahasandana C, et al. Malignant lymphoma in Thailand: changes in the frequency of malignant lymphoma determined from a histopathologic and immunophenotypic analysis of 425 cases at Siriraj Hospital. Cancer 1998;83:1197-204.
Makruasi N, Niparuck P, Sungkanuparph S, Ungkanont A, Kanoksil W, Boonsakan P, et al. Non Hodgkin’s Lymphoma (NHL) in HIV infected patients in Thailand. J Infect Dis Antimicrob Agents 2011;28:5-14.
Katyal N, Wadhwa A, Bollu PC. Multiple cranial neuro pathies in a patient with diffuse large B-cell lymphoma: case report and review of literature. Cureus 2018;10:e2186.