Validation of Functional Assessment of Cancer Therapy with Nasopharyngeal Cancer Subscale (FACT-NP) for Quality of Life in Thai Patients

Authors

  • Thanarpan Peerawong Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Chanon Kongkamol Research Unit of Holistic Health and Safety Management in the Community, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Zhiping Chen Department of Radiotherapy, Cancer Hospital of Jiangxi Province, Qing ShanHu District Nanchang, Jiangxi, 330029, China.
  • Paytai Rordlamool Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Duangjai Sangtawan Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Rungarun Jiratrachu Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.

DOI:

https://doi.org/10.31584/jhsmr.201958

Keywords:

FACT-NP, factor analysis, nasopharyngeal cancer, quality of life

Abstract

Objective: To develop and validate the Thai version of the functional assessment of cancer therapy with nasopharyngeal cancer subscale (FACT-NP) with the abbreviated version of the World Health Organization Quality of Life-BREF instrument (WHOQOL-BREF).
Material and Methods: A cross-sectional study was performed in the Radiology Department between January 2014 and October 2016. Inclusion criteria: nasopharyngeal carcinoma patients aged greater than 18 years. Exclusion criteria: no comprehension of the Thai language, had other cancers (except for skin cancer and diagnosed with impaired cognition and/or overt psychosis), major depression or delirium. After signing the consent form, participants were interviewed and self-completed FACT-NP and WHOQOL-BREF. The structure of the FACT-NP was determined with exploratory factors analysis. The internal reliability of identified domains was evaluated using Cronbach’s alpha. The correlation between domains of the modified FACT-NP and the domains of WHOQOL-BREF were examined with Spearman’s correlation. Known-group validity was determined by comparing patients with different sociodemographic and clinical characteristics using the T-test, Ranksum test and analysis of variance. A p-value of less than 0.05 was considered significant.
Results: This study was terminated early due to a long accrual period. Of the 230 patients included in the study, only 220 completed both FACT-NP and WHOQOL-BREF. Exploratory factor analysis showed an accumulative variance of 0.56 with 4 factors. The internal reliability of modified FACT-NP was 0.92. There was moderate correlation between modified FACT-NP and WHOQOL-BREF. Both the modified FACT-NP and WHOQOL-BREF could identify differences between the groups.
Conclusion: The Thai modified FACT-NP was found to be both valid and reliable for measuring the quality of life in Thai nasopharyngeal cancer patients.

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Published

2019-07-09

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1.
Peerawong T, Kongkamol C, Chen Z, Rordlamool P, Sangtawan D, Jiratrachu R. Validation of Functional Assessment of Cancer Therapy with Nasopharyngeal Cancer Subscale (FACT-NP) for Quality of Life in Thai Patients. J Health Sci Med Res [Internet]. 2019 Jul. 9 [cited 2024 Nov. 23];37(3):247-5. Available from: https://he01.tci-thaijo.org/index.php/jhsmr/article/view/158648

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VOL 37, NO 3 (2019): Jul-Sep

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