The validity and reliability of modified cough transport outcome using slower airflow for assessing mucus viscoelasticity

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Published: Sep 4, 2024
Keywords:
Cough transport, sputum viscosity, chronic respiratory disease, physical therapy, airway mucus clearance,

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Aung Aung Nwe
School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen Province, Thailand. ,Innovation to Improve Cardiopulmonary and Physical Performance (IICP) Research Group, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0009-0007-1311-6853
Nimit Kosura
Department of Physical Therapy, Faculty of Medicine, Prince of Songkla University, Songkla Province, Thailand, Innovation to Improve Cardiopulmonary and Physical Performance (IICP) Research Group, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0000-0001-7660-8555
Chatchai Phimphasak
School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University
Pornthip Barnludech
Unit of Physical Therapy, Department of Rehabilitation, Chulaborn Hospital, Bangkok, Thailand, Innovation to Improve Cardiopulmonary and Physical Performance (IICP) Research Group, Khon Kaen University, Khon Kaen Province, Thailand
Sithu Aung
Department of Tropical Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0009-0008-1160-2089
Worawat Chumpangern
Innovation to Improve Cardiopulmonary and Physical Performance (IICP) Research Group, Khon Kaen University, Khon Kaen Province, Thailand, Pulmonary and Critical Care Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0000-0002-2564-6954
Guntaragorn Hongrattana
Department of Physical Therapy, Khon Kaen Hospital, Khon Kaen Province, Thailand.
https://orcid.org/0000-0001-8097-2464
Sujittra Kluayhomthong
Department of Physical Therapy, School of Integrative Medicine, Mae Fah Luang University,Chiang Rai Province, Thailand
https://orcid.org/0000-0001-9852-8708
Pornanan Domthong
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Khon Kaen Hospital, Khon Kaen Province, Thailand.
Wipa Reechaipichitkul
Pulmonary and Critical Care Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0000-0002-4536-6773
Chatchaya Jaimanee
School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen Province, Thailand., Innovation to Improve Cardiopulmonary and Physical Performance (IICP) Research Group, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0009-0009-1990-4599
Uraiwon Chatchawan
School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0000-0003-2109-0394
Wantana Siritaratiwat
School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0000-0002-6893-7313
Chulee Ubolsakka-Jones
School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen Province, Thailand., Innovation to Improve Cardiopulmonary and Physical Performance (IICP) Research Group, Khon Kaen University, Khon Kaen Province, Thailand.
https://orcid.org/0000-0002-4471-8220

Abstract

Background: The cough transportability technique reflects changes in mucus rheology. However, the necessity of high airflow rates, such as 8 L/s, to carry out this technique limits its utility, as specialized setups or equipment are required.


Objective: This study aims to identify practical alternatives to higher airflow rates and utilize easily accessible equipment, such as mechanical air pumps (2 L/s).


Materials and methods: Mucus simulant gel (MSG) of 4 viscoelasticity and sputum from patients with bronchiectasis were collected and prepared. All samples underwent standard airflow cough transport (sCT) and modified cough transport (mCT). Additionally, three rounds of each MSG and two rounds of sputum underwent mCT.


Results: A Pearson correlation analysis between mCT and sCT revealed very high (r=0.986, p=0.014) and high (r=0.771, p<0.001) in the MSG and the sputum of bronchiectasis patients, respectively. The test-retest reliability of mCT revealed ICCs of 0.997 and 0.926 in the MSG and sputum of patients with bronchiectasis, respectively.>


Conclusion: mCT could be an alternative to sCT, offering a more accessible option for conducting cough transportability

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How to Cite
Aung Aung Nwe, Kosura, N., Phimphasak, C., Barnludech, P. ., Aung, S. ., Chumpangern, W. ., Hongrattana, G. ., Kluayhomthong, S. ., Domthong, P. ., Reechaipichitkul, W. ., Jaimanee, C., Chatchawan, U., Siritaratiwat, W. ., & Ubolsakka-Jones, . C. . (2024). The validity and reliability of modified cough transport outcome using slower airflow for assessing mucus viscoelasticity. Journal of Associated Medical Sciences, 58(1), 1–7. Retrieved from https://he01.tci-thaijo.org/index.php/bulletinAMS/article/view/270422
Issue
Vol. 58 No. 1 (2025): January-April
Section
Research Articles
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Personal views expressed by the contributors in their articles are not necessarily those of the Journal of Associated Medical Sciences, Faculty of Associated Medical Sciences, Chiang Mai University.

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