Effects of aerobic dance exercise on oxidative stress and inflammatory status in abdominal obese women subjects
Article Sidebar
Main Article Content
Abstract
Background: Oxidative stress (OS) and inflammation have been suggested to play a pivotal role in the pathogenesis of chronic diseases. Oxidative stress and inflammatory markers (IM) may be change after regular physical exercise. However, physical activity affects the redox balance and inflammatory markers in abdominal obese (AO) women are still unclear.
Objectives: Aim of this study was to assess OS, total antioxidant and IM on before and after 2 months participation in aerobic dance exercise of 151 obese women.
Materials and methods: A total of 151 obese women [median aged=48.0 years] participated in aerobic dance exercise. All women were subjected to physical and medical examination. Venous blood samples were collected for all biochemical examination.
Results: At the end of the study, the median of glucose, triglyceride, insulin levels, Model assessment of insulin resistance, malondialdehyde, high sensitivity C-reactive protein, tumor necrosis factor α and interleukin-6 were significantly decreased (p<0.05) and high-density lipoprotein-cholesterol and total antioxidant capacity (TAC) were significantly increased (p<0.05) after participation in aerobic dance exercise. Oxidative stress, TAC and IM were involved into the adaptive metabolic changes and redox responses induced by physical exercise aerobic dance.
Conclusion: Exercise aerobic dance reduced the potential OS, IM and protects the higher risk for developing diseases in AO that pathophysiologically linked to OS and IM.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Personal views expressed by the contributors in their articles are not necessarily those of the Journal of Associated Medical Sciences, Faculty of Associated Medical Sciences, Chiang Mai University.
References
Stewart KJ. Role of exercise training on cardiovascular disease in persons who have type 2 diabetes and hypertension. Cardiol Clin. 2004; 22(4): 569-86.
Hu G, Jousilahti P, Barengo NC, Qiao Q, Lakka TA, Tuomilehto J. Physical activity, cardiovascular risk factors, and mortality among Finnish adults with diabetes. Diabetes Care. 2005; 28: 799-805.
Barbieri E, Sestili P. Reactive oxygen species in skeletal muscle signaling. J Signal Transduct. 2012; doi: 10.1155/2012/982794.
Willerson JT, Ridker PM. Inflammation as a cardiovascular risk factor. Circulation. 2004; 109: II2-10.
Bateman LA, Slentz CA, Willis LH, Shields AT, Piner LW, Bales CW, et al. Comparison of aerobic versus resistance exercise training effects on metabolic syndrome (from the Studies of a Targeted Risk Reduction Intervention Through Defined Exercise -STRRIDE-AT/RT). Am. J. Cardiol. 2011; 108(6): 838-44.
Huffman KM, Slentz CA, Bateman LA, Thompson D, Muehlbauer MJ, Bain JR, et al. Exercise induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity. Diabetes Care. 2011; 34(1): 174-6.
Slentz CA, Bateman LA, Willis LH, Granville EO, Piner LW, Samsa GP, et al. Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised trial. Diabetiologia. 2016; 59 (10): 2088-98.
Gleeson M, Bishop NC, Stensel DJ, Lindley MR, Mastana SS, Nimmo MA. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat Rev Immunol. 2011; 11(9): 607-15.
Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, et al. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011; 17(17): 6-63.
Tangvarasittichai S, Pongthaisong S, Tangvarasittichai O. Tumor Necrosis Factor-α, Interleukin-6, C-Reactive Protein Levels and Insulin Resistance Associated with Type 2 Diabetes in Abdominal Obesity Women. Ind J Clin Biochem. 2016; 31(1): 68-74.
Alberti KG, Zimmet P, Shaw J. Metabolic syndrome-a new world-wide definition. A consensus statement from the International Diabetes Federation. Diabet Med. 2006; 23: 469-80.
World Health Organization-International Society of Hypertension. World Health Organization-International Society of hypertension guidelines for the management of hypertension. Guidelines Subcommittee. J Hypertens. 1999; 17(2): 151-83.
Duncan MH, Singh BM, Wise PH, Carter G, Alaghband-Zadeh J. A simple measure of insulin resistance. Lancet. 1995; 346: 120-1.
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985; 28: 412-9.
Haffner SM, Kennedy E, Gonzalez C, Stern MP, Miettinen H. A prospective analysis of the HOMA model. The Mexico City Diabetes Study. Diabetes Care. 1996; 19: 1138-41.
Tangvarasittichai S, Poonsub P, Tangvarasittichai O, Sirigulsatien V. Serum levels of malondialdehyde in type 2 diabetes mellitus Thai subjects. Siriraj Med J. 2009; 61: 20-3.
Miller NJ, Rice-Evans C, Davies MJ, Gopinathan V, Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin Sci (Lond). 1993; 84: 407-12.
Dvora´kova´-Lorenzova´ A, Sucha´nek P, Havel PJ, Stavek P, Karasova L, Valenta Z, et al. The decrease in C-reactive protein concentration after diet and physical activity induced weight reduction is associated with changes in plasma lipids, but not interleukin-6 or adiponectin. Metabolism. 2006; 55: 359-65.
Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 2000; 87: 840-4.
Morrell CN. Reactive oxygen species: finding the right balance. Circ Res. 2008; 103: 571-2.
Mercken EM, Hageman GJ, Schols AM, Akkermans MA, Bast A, Wouters EF. Rehabilitation decreases exercise-induced oxidative stress in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2005; 172: 994-1001.
Cases N, Sureda A, Maestre I, Tauler P, Aquilo A, CoÂrdova A, et al. Response of antioxidant defences to oxidative stress induced by prolonged exercise: antioxidant enzyme gene expression in lymphocytes. Eur J Appl Physiol. 2006; 98: 263-9.
Niskanen L, Laaksonen DE, Nyysso¨nen K, Punnonen K, Valkonen VP, Fuentes R, et al. Inflammation, abdominal obesity, and smoking as predictors of hypertension. Hypertension. 2004; 44: 859-65.
Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: An American Heart Association/ National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005; 112: 2735-52.
Laaksonen DE, Niskanen L, Nyysso¨nen K, Punnonen K, Tuomainen TP, Valkonen VP, et al. C-reactive protein and the development of the metabolic syndrome and diabetes in middleaged men. Diabetologia. 2004; 47: 1403-10.
Ridker PM, Buring JE, Cook NR, Rifai N. C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women. Circulation. 2003; 107: 391-7.
Giannopoulou I, Ploutz-Snyder LL, Carhart R, Weinstock RS, Fernhall B, Goulopoulou S, et al. Exercise is required for visceral fat loss in postmenopausal women with type 2 diabetes. J Clin Endocrinol Metab. 2005; 90(3): 1511-8.
Ross R, Bradshaw AJ. The future of obesity reduction: beyond weight loss. Nat Rev Endocrinol. 2009; 5(6): 319-26.
Forsythe LK, Wallace JMW, Livingstone MBE. Obesity and inflammation: the effects of weight loss. Nutr Res Rev. 2008; 21(2): 117-33.
Trøseid M, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, et al. Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J. 2004; 25(4): 349-55.
Lambert CP, Wright NR, Finck BN, Villareal DT. Exercise but not diet-induced weight loss decreases skeletal muscle inflammatory gene expression in frail obese elderly persons. J Appl Physiol. 2008; 105(2): 473-78.
Mujumdar PP, Duerksen-Hughes PJ, Firek AF, Hessinger DA. Long-term, progressive, aerobic training increases adiponectin in middle-aged, overweight, untrained males and females. Scand J Clin Lab Invest. 2011; 71(2): 101-7.
Lee S, Park Y, Dellsperger KC, Zhang C. Exercise training improves endothelial function via adiponectin dependent and independent pathways in type 2 diabetic mice. Am. J. Physiol-Heart Circ Physiol. 2011; 301(2): H306-H314.
Yu Z, Ye X, Wang J, Qi Q, Franco OH, Rennie KL, et al. Associations of physical activity with inflammatory factors, adipocytokines, and metabolic syndrome in middle-aged and older chinese people. Circulation. 2009; 119(23): 2969-77.
Hui X, Lam KS, Vanhoutte PM, Xu A. Adiponectin and cardiovascular health: an update. Br J Pharmacol. 2012; 165(3): 574-90.
Andrade-Oliveira V, Câmara NOS, Moraes-Vieira PM. Adipokines as drug targets in diabetes and underlying disturbances. J Diabetes Res. 2015; 681612: 11.
Beavers KM, Brinkley TE, Nicklas BJ. Effect of exercise training on chronic inflammation. Clin Chim Acta. 2010; 411(11-12): 785-93.
Rauramaa R, Halonen P, Väisänen SB, Lakka TA, Schmidt-Trucksäss A, Berg A, et al. Effects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO study: a six-year randomized, controlled trial. Ann. Intern. Med. 2004; 140(12): 1007-14.
Marcell TJ, McAuley KA, Traustadóttir T, Reaven PD. Exercise training is not associated with improved levels of C-reactive protein or adiponectin. Metab Clin Exp. 2005; 54(4): 533-41.
Kelley GA, Kelley KS. Effects of aerobic exercise on C-reactive protein, body composition, and maximum oxygen consumption in adults: a meta-analysis of randomized controlled trials. Metab Clin Exp. 2006; 55(11): 1500-7.