Reinfection of SARS CoV-2 in patients with relapse of symptoms after clinical recovery: A Case Series
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Abstract
Background: It has been more than a year, and still, we are battling with a novel
coronavirus (SARS-COV-2). Initially, the interim guidelines by the World health organization (WHO) stated that infection ranges from asymptomatic to critical life-threatening pneumonia with the symptomatology of fever, cough and breathing difficulty.
Objectives: To observe the reinfection of SARS CoV-2 in patients with relapse of symptoms after clinical recovery.
Materials and methods: Three cases were observed during the isolation period. Reverse transcription polymerase chain reaction (RT-PCR) and severity of similar symptoms in the fourth week from the onset was monitored.
Results: All the three patients had health care exposure, and which pointed us towards health care associated reinfection could be a possible cause of step-up in the symptom severity.
Conclusion: Reinfection by SARS CoV-2 can be considered in patients with relapse of symptoms after clinical recovery after natural infections.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Personal views expressed by the contributors in their articles are not necessarily those of the Journal of Associated Medical Sciences, Faculty of Associated Medical Sciences, Chiang Mai University.
References
Mehta Y, Chaudhry D, Abraham OC, Chacko J, Divatia J, Jagiasi B, et al. Critical Care for COVID-19 Affected Patients: Position Statement of the Indian Society of Critical Care Medicine. Indian J Crit Care Med. 2020; 24(4): 222-41. doi: 10.5005/jp-journals-10071-23395.
Adukia SA, Ruhatiya RS, Maheshwarappa HM, Manjunath RB, Jain GN. Extrapulmonary Features of COVID-19: A Concise Review. Indian J Crit Care Med. 2020; 24(7): 575-80. doi: 10.5005/jp-journals-10071-23476.
COVID-19 Treatment Guidelines Panel. Coronavirus disease 2019 (COVID-19) treatment guidelines. 2020 [cited 2022 January 26]. Available from:https://files.covid19treatmentguidelines.nih.gov/guidelines/covid19treatmentguidelines.pdf.
RECOVERY Collaborative Group, Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, et al. Dexamethasone in Hospitalized Patients with Covid-19. N Engl J Med.2021; 384(8), 693-704. https://doi.org/10.1056/NEJMoa2021436.
Grasselli G, Tonetti T, Protti A, Langer T, Girardis M, Bellani G, et al. Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study. Lancet Respir Med. 2020; 8(12): 1201-8. doi: 10.1016/S2213-2600(20)30370-2.
Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review. JAMA. 2020; 324(8): 782-93. doi: 10.1001/jama.2020.12839.
Bi Q, Wu Y, Mei S, Ye C, Zou X, Zhang Z, et al. Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study. Lancet Infect Dis. 2020; 20(8): 911-9. doi: 10.1016/S1473-3099(20)30287-5.
World Health Organization. Transmission of SARS-CoV-2: implications for infection prevention precautions: scientific brief. 2020 [Cited 2022 January 26]. Available from: https://apps.who.int/iris/handle/10665/333114.
Hansen CH, Michlmayr D, Gubbels SM, Mølbak K, Ethelberg S. Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study. Lancet. 2021; 397(10280): 1204-12. doi: 10.1016/S0140-6736(21)00575-4.
Boyton RJ, Altmann DM. Risk of SARS-CoV-2 reinfection after natural infection. Lancet. 2021; 397(10280): 1161-3. doi: 10.1016/S0140-6736(21)00662-0.
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020; 323(11): 1061-9. doi: 10.1001/jama.2020.1585.
Kuanar A, Kabi SK, Satapathy S, Mishra S, Bhuyan R, Kar D. Corona Virus-A review concerns about the present scenario. Ann. Romanian Soc. Cell Biol. 2021; 25(2): 1301-15.
Taribagil P, Creer D, Tahir H. 'Long COVID' syndrome. BMJ Case Rep. 2021; 14(4): e241485. doi: 10.1136/bcr-2020-241485.