Predictors of 30-Day Mortality of Cardiogenic Shock Complicating ST-Elevation Myocardial Infarction at Trang Hospital
Keywords:
Mortality, cardiogenic shock, ST-elevation myocardial infarctionAbstract
Background: ST-elevation myocardial infarction is a major health problem in all countries. The presence of cardiogenic shock increases mortality in this patient population.
Objective: To study the mortality rate and predictors of 30-day mortality of patients with acute ST segment elevation myocardial infarction with cardiogenic shock at Trang Hospital.
Materials and Methods: This is a retrospective study of patients with acute ST segment elevation myocardial infarction with cardiogenic shock who were admitted to Trang Hospital from January 2021 to December 2023.
Results: A total of 83 patients were included in this study. The results showed that 30-day mortality rate was 37.4% (31 patients). Factors that significantly affected the mortality rate were eGFR (AOR = 0.94, 95% CI = 0.90-0.97, P = <0.001), Ventricular arrhythmia (VT/VF) (AOR = 4.69, 95% CI = 1.26-17.51, P = 0.021), and the number of inotropic drugs. (AOR = 2.88, 95% CI = 1.13-7.38, P = 0.027)
Conclusions: Patients with acute ST-segment elevation myocardial infarction with cardiogenic shock admitted to Trang Hospital had a mortality rate of 37.4%. eGFR, Ventricular arrhythmia (VT/VF) and the number of inotropic drugs were associated with increased mortality.
References
แนวเวชปฏิบัติการดูแลรักษาผู้ป่วยภาวะหัวใจขาดเลือดเฉียบพลัน พ.ศ.2563 สมาคมแพทย์โรคหัวใจแห่งประเทศไทย ในพระบรมราชูปถัมภ์: ISBN : 978-616-8023-12-9
Goldberg R.J., Samad N.A., Yarzebski J., Gurwitz J., Bigelow C., Gore J.M. "Temporal trends in cardiogenic shock complicating acute myocardial infarction". N Engl J Med . 1999;340:1162-1168.
Kolte D., Khera S., Aronow W.S., et al. "Trends in incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction in the United States". J Am Heart Assoc . 2014;3:E000590.
Aissaoui N., Puymirat E., Delmas C., et al. "Trends in cardiogenic shock complicating acute myocardial infarction". Eur J Heart Fail . 2020;22:664-672
N.K. Kapur, K.L. Thayer, E. Zweck Cardiogenic shock in the setting of acute myocardial infarction Methodist Debakey Cardiovasc J, 16 (1) (2020), pp. 16-21, 10.14797/mdcj-16-1-16
J.S. Hochman, L.A. Sleeper, J.G. Webb, et al. Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should we emergently revascularize occluded coronaries for cardiogenic shock N Engl J Med, 341 (9) (1999), pp. 625-634, 10.1056/NEJM199908263410901
Sterling, L, Fernando, S, Talarico, R. et al. Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction. JACC. 2023 Sep, 82 (10) 985–995. https://doi.org/10.1016/j.jacc.2023.06.026
Kayaert P, Coeman M, Demolder A, et al. Mortality in STEMI Patients With Cardiogenic Shock: Results From a Nationwide PCI Registry and Focus on Left Main PCI. J Invasive Cardiol. 2022 Feb;34(2):E142-E148. doi: 10.25270/jic/21.00148. PMID: 35100557.
Tsai TH, Chai HT, Sun CK, et al. Comparison of 30-day mortality between anterior-wall versus inferior-wall ST-segment elevation myocardial infarction complicated by cardiogenic shock in patients undergoing primary coronary angioplasty. Cardiology. 2010;116(2):144-50. doi: 10.1159/000317252. Epub 2010 Jul 3. PMID: 20606428.
Muzafarova T, Motovska Z, Hlinomaz O, et al. The Prognosis of Cardiogenic Shock Following Acute Myocardial Infarction-an Analysis of 2693 Cases From a Prospective Multicenter Registry. Dtsch Arztebl Int. 2023 Aug 7;120(31-32):538-539. doi: 10.3238/arztebl.m2023.0102. PMID: 37721142; PMCID: PMC10534133.
Lin, W.; Yip, A.C.L.; Cherian, R. et al. Predictors of Mortality in Acute Myocardial Infarction Complicated by Cardiogenic Shock despite Intra-Aortic Balloon Pump: Opportunities for Advanced Mechanical Circulatory Support in Asia. Life 2024, 14, 577. https://doi.org/10.3390/life14050577
Vicent L, Velásquez-Rodríguez J, Valero-Masa MJ, Díez-Delhoyo F, González-Saldívar H, Bruña V, et al. Predictors of high Killip class after ST segment elevation myocardial infarction in the era of primary reperfusion. Int J Cardiol. 2017 Dec 1;248:46-50. doi:10.1016/j.ijcard.2017.07.038. PMID: 28942880.
Venkatason P, Zubairi YZ, Wan Ahmad WA, et al. In-hospital mortality of cardiogenic shock complicating ST-elevation myocardial infarction in Malaysia: a retrospective analysis of the Malaysian National Cardiovascular Database (NCVD) registryBMJ Open 2019;9:e025734. doi: 10.1136/bmjopen-2018-025734
Kochan, A.; Lee, T.; Moghaddam, N.; Milley, G.; Singer, J.; Cairns, J.A.; et al. Reperfusion Delays and Outcomes Among Patients with ST-Segment–Elevation Myocardial Infarction with and Without Cardiogenic Shock. Circ. Cardiovasc. Interv. 2023, 16, e012810
Saleiro C, Teixeira R, De Campos D, Lopes J, Oliveiros B, Costa M, et al. Glycoprotein IIb/IIIa inhibitors for cardiogenic shock complicating acute myocardial infarction: a systematic review, meta-analysis, and meta-regression. J Intensive Care. 2020 Nov 11;8(1):85. doi: 10.1186/s40560-020-00502-y. PMID: 33292610; PMCID: PMC7656750.
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นลิขสิทธิ์ของมหาราชนครศรีธรรมราชเวชสาร หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษรจากวารสารมหาราชนครศรีธรรมราชเวชสาร ก่อนเท่านั้น