Factors associated with coronary artery disease among patients with type 2 diabetes mellitus in Srinakhon Hospital, Sukhothai Province

Abstract

The purpose of this case-control study was to study factors associated with coronary artery disease among patients with type 2 diabetes mellitus (T2DM) in Srinakhon Hospital, Sukhothai Province. The samples were 140 patients with T2DM, which were selected using sampling without replacement technique. The data collection was collected from medical records of patients with T2DM admitted to Srinakhon Hospital between 2017-2019, and analyzed by using the frequency distribution, percentage, Chi-square test, Fisher's exact test, and Crude Odds ratio.

The results revealed that the factors associated with coronary artery disease among patients with T2DM including male sex (Crude OR = 2.26; 95%CI: 1.12-4.58; p-value = 0.022), age ≥ 60 years (Crude OR = 2.97; 95%CI: 1.47-5.98; p-value = 0.002), smoking (Crude OR = 2.68; 95%CI: 1.08-6.67; p-value = 0.029), drinking alcohol (Crude OR = 2.71; 95%CI: 1.13-6.48; p-value = 0.022), irregular attendance to follow-up visits (OR = 3.35; 95%CI: 1.37-8.60; p-value = 0.009), use of aspirin (Crude OR = 2.70; 95%CI: 1.36-5.35; p-value = 0.004), use of enalapril or losartan (Crude OR = 3.05; 95%CI: 1.53-6.06; p-value = 0.001), systolic blood pressure ≥ 140 mmHg (Crude OR = 4.01; 95%CI: 1.71-9.38; p-value < 0.001), microalbumin level of 31-300 gm/dl (Crude OR = 5.23; 95%CI: 2.11-12.96; p-value < 0.001), low density lipoprotein-cholesterol level of ≥ 100 mg/dl (Crude OR = 2.45; 95%CI: 1.16-5.17; p-value = 0.017), hypertension (Crude OR = 8.00; 95%CI: 3.06-20.92; p-value < 0.001), and dyslipidemia (Crude OR = 6.62; 95%CI: 1.83-23.90; p-value = 0.001). The study implicated thathealthcare provider should be considered on risk factors to prevent of coronary artery disease among patients with T2DM.