Managing Osteoporosis and Fracture Prevention in Chronic Kidney Disease
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Abstract
Patients with chronic kidney disease (CKD) are at risk of osteoporosis and fracture compared with normal populations, especially after hip fracture contributing to morbidity, cost of treatment, and high mortality. Therefore, fracture risk assessment and early treatment to prevent fracture are important. The complex mechanisms of bone fragility in CKD require different approaches to treat and prevent fracture unlike in normal populations. In addition, current available anti-osteoporosis drugs still have insufficient evidence in efficacy and safety in CKD population. This review focused on current evidence in fracture risk assessment and treatment options of osteoporosis among patients with CKD to prevent fractures.
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