Association between unvaccinated COVID-19 and COVID-19 mortality in Udonthani province

Abstract

Coronavirus 2019 (COVID-19) outbreak was the cause of many COVID-19 patients and deaths. The Thai government have a policy for people to get vaccinated since April 2021 to reduce its severity. However, mortality in the 607 group became higher. This research aimed at investigating the association between unvaccinated COVID-19 and COVID-19 mortality in Udonthani Province and finding out the COVID-19 mortality. This is a retrospective cohort study conducted from monitoring registered patients from January 1 to August 31,2022 totaled 6,921 individuals over a 30-day period to ascertain treatment outcomes. Generalized Linear Model (GLM) was used for association analysis, and Adjusted RR with 95% confidence intervals was presented. The finding revealed that COVID-19 mortality in the unvaccinated was 3.1% (95%CI : 2.60-3.76); however, it became lower after getting the 2^nd dose and boosters (3^rd and 4^th doses). The unvaccinated was significantly associated with the mortality (p-value < 0.001). In other words, when controlling the effect from age and chronic disease variables in the last equation, the unvaccinated was 1.9 times more likely to have mortality than the vaccinated (Adjusted RR 1.9, 95%CI : 1.49-2.50). As a result, public health services should provide vaccination services against COVID-19. Proactive among the elderly and those with underlying medical conditions Increase access to COVID-19 immunization services Under the standard, the vaccine service continues.