A comparison of Normal Saline and Ringer’s lactate solution for fluid resuscitation and mortality rate in adult patients with sepsis and septic shock in Nakhon Nayok Hospital

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Wiratchanee Wongwilai


Sepsis and Septic Shock are critical conditions in hospitals. It is a common condition found in hospitals. It is also a significant problem in the public health system because it has a high mortality rate and is the primary cause of death worldwide, even in Nakhon Nayok Hospital, where the researcher works. Practice that is popular and accepted all over the world is the Surviving Sepsis Campaign, which found that giving fluids to maintain a standard circulatory system is the main factor and essential factor in reducing the mortality rate of Sepsis patients. However, there is still a debate about the most suitable fluid for resuscitation in Sepsis patients. The researcher collected medical records from patients diagnosed with sepsis/severe sepsis/septic shock and admitted to Nakhon Nayok Hospital. In the period from Jan. 2021 - May 2023. Recorded type of fluid for resuscitation NSS or RLS, the fluid volume in 1 hour after diagnosis. Comparison of mortality rate, the incidence of renal failure at the end of treatment and 30 days after treatment, and length of stay in the Hospital between two groups of patients who received NSS or RLS. The mortality and acute renal failure rates after treatment between the NSS and RLS groups in Sepsis/Septic shock in Nakhon Nayok Hospital differed. However, the length of stay at Nakhon Nayok Hospital was different. The RLS group had a more extended hospital stay than the NSS group.

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Wongwilai W. A comparison of Normal Saline and Ringer’s lactate solution for fluid resuscitation and mortality rate in adult patients with sepsis and septic shock in Nakhon Nayok Hospital. JMPH4 [Internet]. 2024 Jun. 11 [cited 2024 Jul. 17];14(2):105-1. Available from: https://he01.tci-thaijo.org/index.php/JMPH4/article/view/264342
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