Spatial autocorrelation analysis of diarrhea incidence in Bandung City, Indonesia in 2024 10.55131/jphd/2026/240107
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Abstract
Diarrhea remains a significant public health issue worldwide. The World Health Organization (WHO) estimates that diarrhea accounts for approximately 1.7 billion cases annually, making it a leading cause of child mortality. The morbidity rate for diarrhea in Bandung City across all age groups was 25 per 1,000 population in 2019. This study analyzes the spatial autocorrelation of diarrhea incidence in Bandung City, Indonesia, using Moran’s index. A retrospective spatial analysis was conducted on 896 diarrhea cases recorded at Harapan Bunda Hospital, Bandung, from January 1 to June 30, 2024. Spatial autocorrelation was assessed using Moran’s I, with spatial units defined at the district level. The analysis incorporated ICD-10 classifications, including A06 (amoebiasis), A09 (diarrhea and gastroenteritis due to infectious causes), and O99.6 (digestive diseases complicating pregnancy). The results of autocorrelation were as follows: mild or some dehydration by age (Moran’s I = 0.396, p = 0.001), unspecified amoebiasis (Moran’s I = 0.421, p = 0.000), amoebiasis (Moran’s I = 0.508, p = 0.000), diarrhea and gastroenteritis of presumed infectious origin (Moran’s I = 0.450, p = 0.000), unspecified dehydration status by age (Moran’s I = 0.302, p = 0.000), digestive system diseases complicating pregnancy, childbirth, and the puerperium (Moran’s I = -0.450 , p = 0.000). These findings indicated a clustered distribution pattern, suggesting that diarrhea incidence in one location correlates with cases in surrounding locations. This study recommends targeted interventions for high-risk clusters, such as community-based health programs and environmental sanitation improvements.
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References
Diarrhoeal disease [Internet]. 2024 [Cited 2024]. Available at: https:// www.who.int/news-room/fact-sheets/ detail/diarrhoeal-disease
Rafiuddin AT, Purwanty M. Factors Associated With The Incidence Of Diarrhea In Toddlers In The Working Area Of Puuwatu Health Center, Kendari City. 1 2020; 3(1): 65–75. Available at: https://doi.org/10.36566/ mjph/Vol3.Iss1/140
Dinas Kesehatan Kota Bandung. Bandung City Health Profile Year 2020 [Internet]. 2020. Available at: https://dinkes.bandung.go.id/download/profil-kesehatan-kota-bandung-2020/
Chu C, Rotondo-Trivette S, Michail S. Chronic diarrhea. Curr Probl Pediatr Adolesc Health Care 2020; 50(8): 100841. Available at: https://doi.org/ 10.1016/j.cppeds.2020.100841
Camilleri M, Sellin JH, Barrett KE. Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea. Gastroenterology 2017; 152(3): 515-532.e2. Available at: https://doi.org/10.1053/j.gastro.2016.10.014
Ferris A, Gaisinskaya P, Nandi N. Approach to Diarrhea. Prim Care 2023; 50(3): 447–59. Available at: https://doi.org/10.1016/j.pop.2023.03.010
Ryan MJ, Schloter M, Berg G, Kostic T, Kinkel LL, Eversole K, et al. Development of Microbiome Biobanks - Challenges and Opportunities. Trends Microbiol 2021; 29(2): 89–92. Available at: https://doi.org/10.1016/ j.tim.2020.06.009
Rego R, Watson S, Gill P, Lilford R. The impact of diarrhoea measurement methods for under 5s in low- and middle-income countries on estimated diarrhoea rates at the population level: A systematic review and meta-analysis of methodological and primary empirical studies. Trop Med Int Health 2022; 27(4): 347–68. Available at: https://doi.org/10.1111/tmi.13739
Fan Y, Pedersen O. Gut microbiota in human metabolic health and disease. Nat Rev Microbiol 2021; 19(1): 55–71. Available at: https://doi.org/10.1038/ s41579-020-0433-9
Raza O, Mansournia MA, Rahimi Foroushani A, Holakouie-Naieni K. Exploring spatial dependencies in the prevalence of childhood diarrhea in Mozambique using global and local measures of spatial autocorrelation. Med J Islam Repub Iran 2020; 34: 59. Available at: https://doi.org/10.34171/ mjiri.34.59
Almasi A, Zangeneh A, Ziapour A, Saeidi S, Teimouri R, Ahmadi T, et al. Investigating Global Spatial Patterns of Diarrhea-Related Mortality in Children Under Five. Front Public Health [Internet] 2022 [Cited 2025]; 10. Available at: https://doi.org/10.3389/ fpubh.2022.861629
Syukri M, Halim R. Spatial Analysis to Identify Hotspot of Diarrhea Among Children under Five Years in 154 Districts/Cities in Sumatera Island. Indonesian Journal of Global Health Research 2023; 5(1): 111–20. Available at: https://doi.org/10.37287/ijghr.v5i1. 1777
Wahyudi T, Yuniar P, Rahmaniati M. Spatial Autocorrelation of Diarrhea Cases in West Java Province in 2023. Media Publikasi Promosi Kesehatan Indonesia (MPPKI) 2024; 7(9): 2368–76. Available at: https://doi.org/ 10.56338/mppki.v7i9.5973
Jandhyala SM, Talukdar R, Subramanyam C, Vuyyuru H, Sasikala M, Reddy DN. Role of the normal gut microbiota. World J Gastroenterol 2015; 21(29): 8787–803. Available at: https://doi.org/10.3748/wjg.v21.i29.8787
Yin J, Li Y, Han H, Ma J, Liu G, Wu X, et al. Administration of Exogenous Melatonin Improves the Diurnal Rhythms of the Gut Microbiota in Mice Fed a High-Fat Diet. mSystems 2020; 5(3): e00002-20. Available at: https:// doi.org/10.1128/mSystems.00002-20
Gresse R, Chaucheyras-Durand F, Fleury MA, Van de Wiele T, Forano E, Blanquet-Diot S. Gut Microbiota Dysbiosis in Postweaning Piglets: Understanding the Keys to Health. Trends Microbiol 2017; 25(10): 851–73. Available at: https://doi.org/ 10.1016/j.tim.2017.05.004
Torres-Fuentes C, Schellekens H, Dinan TG, Cryan JF. The microbiota-gut-brain axis in obesity. Lancet Gastroenterol Hepatol 2017; 2(10): 747–56. Available at: https://doi.org/ 10.1016/S2468-1253(17)30147-4
Carvalho S, Magalhães M de AFM, Medronho R de A. Analysis of the spatial distribution of dengue cases in the city of Rio de Janeiro, 2011 and 2012. Rev Saude Publica 2017; 51: 79. Available at: https://doi.org/10.11606/ S1518-8787.2017051006239
Iryanto AA, Firmansyah YW, Widyantoro W, Zolanda A. Spatial Patterns of Environmental Sanitation Factors as Determinants of Toddlers’ Diarrhea in Pauh District, Padang City in 2021. JURNAL KESEHATAN LINGKUNGAN 2022; 14(2): 71–81. Available at: https://doi.org/10.20473/ jkl.v14i2.2022.71-81
Firmansyah YW, Setiani O, Darundiati YH, Joko T, Raharjo M. Water Pollution Index and The Distribution of Waterborne Diseases on The East Flood Canal, Semarang City : An Analysis Spatial. Jurnal Aisyah : Jurnal Ilmu Kesehatan 2021; 6(3): 569–78. Available at: https://doi.org/10.30604/ jika.v6i3.701
George CM, Perin J, Neiswender de Calani KJ, Norman WR, Perry H, Davis TP, et al. Risk Factors for Diarrhea in Children under Five Years of Age Residing in Peri-urban Communities in Cochabamba, Bolivia. Am J Trop Med Hyg 2014; 91(6): 1190–6. Available at: https://doi.org/10.4269/ajtmh.14-0057
Ghosh K, Chakraborty AS, Mog M. Prevalence of diarrhoea among under five children in India and its contextual determinants: A geo-spatial analysis. Clinical Epidemiology and Global Health 2021; 12: 100813. Available at: https://doi.org/10.1016/j.cegh.2021.100813
Azanaw J, Malede A, Yalew HF, Worede EA. Determinants of diarrhoeal diseases among under-five children in Africa (2013–2023): a comprehensive systematic review highlighting geographic variances, socioeconomic influences, and environmental factors. BMC Public Health 2024; 24(1): 2399. Available at: https://doi.org/10.1186/ s12889-024-19962-0
Wenzl HH. Diarrhea in chronic inflammatory bowel diseases. Gastroenterol Clin North Am 2012; 41(3): 651–75. Available at: https:// doi.org/10.1016/j.gtc.2012.06.006
Corgneau M, Scher J, Ritie-Pertusa L, Le DTL, Petit J, Nikolova Y, et al. Recent advances on lactose intolerance: Tolerance thresholds and currently available answers. Crit Rev Food Sci Nutr 2017; 57(15): 3344–56. Available at: https://doi.org/10.1080/10408398. 2015.1123671
Zhong Y, Priebe MG, Vonk RJ, Huang C-Y, Antoine J-M, He T, et al. The role of colonic microbiota in lactose intolerance. Dig Dis Sci 2004; 49(1): 78–83. Available at: https://doi.org/ 10.1023/b:ddas.0000011606.96795.40
Clasen T, Pruss-Ustun A, Mathers CD, Cumming O, Cairncross S, Colford JM. Estimating the impact of unsafe water, sanitation and hygiene on the global burden of disease: evolving and alternative methods. Trop Med Int Health 2014; 19(8): 884–93. Available at: https://doi.org/10.1111/tmi.12330
Prüss-Ustün A, Wolf J, Bartram J, Clasen T, Cumming O, Freeman MC, et al. Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes: An updated analysis with a focus on low- and middle-income countries. Int J Hyg Environ Health 2019; 222(5): 765–77. Available at: https://doi.org/10.1016/ j.ijheh.2019.05.004
Alsan M, Goldin C. Watersheds in Child Mortality: The Role of Effective Water and Sewerage Infrastructure, 1880 to 1920. Journal of Political Economy 2018; 127. Available at: https://doi.org/10.1086/700766
Dangour AD, Watson L, Cumming O, Boisson S, Che Y, Velleman Y, et al. Interventions to improve water quality and supply, sanitation and hygiene practices, and their effects on the nutritional status of children. Cochrane Database Syst Rev 2013;(8): CD009382. Available at: https:// doi.org/10.1002/14651858.CD009382.pub2
Fuller JA, Eisenberg JNS. Herd Protection from Drinking Water, Sanitation, and Hygiene Interventions. Am J Trop Med Hyg 2016; 95(5): 1201–10. Available at: https://doi.org/ 10.4269/ajtmh.15-0677
Chen J, Wan C-M, Gong S-T, Fang F, Sun M, Qian Y, et al. Chinese clinical practice guidelines for acute infectious diarrhea in children. World J Pediatr 2018; 14(5): 429–36. Available at: https://doi.org/10.1007/s12519-018-0190-2
Shane AL, Mody RK, Crump JA, Tarr PI, Steiner TS, Kotloff K, et al. 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea. Clin Infect Dis 2017; 65(12): e45–80. Available at: https://doi.org/10.1093/cid/cix669
Navaneethan U, Giannella RA. Mechanisms of infectious diarrhea. Nat Clin Pract Gastroenterol Hepatol 2008; 5(11): 637–47. Available at: https:// doi.org/10.1038/ncpgasthep1264