A statistical assessment of awareness on antimicrobial resistance and antibiotics use attitude among the university students in Karachi, Pakistan 10.55131/jphd/2022/200207
Main Article Content
Abstract
The survival instincts of microbials in response to antibiotics have revolutionized the prescribing practices. Antimicrobials must be used with great care and general public needs awareness of this burning issue. The objective of this study is to highlight the perception of university students with respect to antimicrobial resistance awareness and subsequently their attitude towards using antibiotics. The respondents in the study were selected on the basis of their education background from both healthcare and non-healthcare professions. The study was conducted on 1592 university students and data were collected using questionnaire based on Likert scale. The results were evaluated using Pearson’s Chi-square test and the association between various factors was calculated by Cramer’s V. The awareness level of students from the non-healthcare background, as an approximate of general public, was found to be significantly lower than healthcare students, thus enabling healthcare students to portray a more responsible attitude towards antibiotics use as compared to non-healthcare students (p<0.05). The level of awareness in non-healthcare students as compared to healthcare students, used as an approximate of the general public, indicates a gap in awareness campaigns about antimicrobial resistance for general public. It is recommended that the responsible use of antibiotics should be encouraged by awareness campaigns for both healthcare personnel and general public.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
Bloom DE, Black S, Salisbury D, Rappuoli R. Antimicrobial resistance and the role of vaccines. Proceedings of the National Academy of Sciences. 2018;115(51):12868-71.
Waseem H, Ali J, Sarwar F, Khan A, Rehman HSU, Choudri M, et al. Assessment of knowledge and attitude trends towards antimicrobial resistance (AMR) among the community members, pharmacists/pharmacy owners and physicians in district Sialkot, Pakistan. Antimicrobial Resistance & Infection Control. 2019;8(1):67.
Schrader SM, Vaubourgeix J, Nathan C. Biology of antimicrobial resistance and approaches to combat it. Science translational medicine. 2020;12(549).
Laxminarayan R, Van Boeckel T, Frost I, Kariuki S, Khan EA, Limmathurotsakul D, et al. The Lancet Infectious Diseases Commission on antimicrobial resistance: 6 years later. The Lancet Infectious Diseases. 2020;20(4):e51-e60.
Christaki E, Marcou M, Tofarides A. Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence. Journal of molecular evolution. 2020;88(1):26-40.
Whittaker A, Lohm D, Lemoh C, Cheng AC, Davis M. Investigating Understandings of Antibiotics and Antimicrobial Resistance in Diverse Ethnic Communities in Australia: Findings from a Qualitative Study. Antibiotics. 2019;8(3):135.
Machowska A, Stålsby Lundborg C. Drivers of irrational use of antibiotics in Europe. International journal of environmental research and public health. 2019;16(1):27.
Mendelson M, Matsoso MP. The World Health Organization global action plan for antimicrobial resistance. SAMJ: South African Medical Journal. 2015;105(5):325-.
Ha TV, Nguyen AMT, Nguyen HST. Public awareness about antibiotic use and resistance among residents in highland areas of Vietnam. BioMed research international. 2019;2019.
Kanneppady SS, Oo AM, Lwin OM, Al-Abed A-AAA, Kanneppady SK. Knowledge, attitude, and awareness of antibiotic resistance among medical students. Archives of Medicine and Health Sciences. 2019;7(1):57.
Awad AI, Aboud EA. Knowledge, attitude and practice towards antibiotic use among the public in Kuwait. PloS one. 2015;10(2).
Klein EY, Van Boeckel TP, Martinez EM, Pant S, Gandra S, Levin SA, et al. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proceedings of the National Academy of Sciences. 2018;115(15):E3463-E70.
Laxminarayan R, Matsoso P, Pant S, Brower C, Røttingen J-A, Klugman K, et al. Access to effective antimicrobials: a worldwide challenge. The Lancet. 2016;387(10014):168-75.
Seid MA, Hussen MS. Knowledge and attitude towards antimicrobial resistance among final year undergraduate paramedical students at University of Gondar, Ethiopia. BMC infectious diseases. 2018;18(1):312.
Prestinaci F, Pezzotti P, Pantosti A. Antimicrobial resistance: a global multifaceted phenomenon. Pathogens and global health. 2015;109(7):309-18.
WHO. Antibiotic resistance: Multi-country public awareness survey [Internet]. Available from:https://appswhoint/iris/bitstream/handle/10665/194460/9789241509817_engpdf;jsessionid=47813E9599BE5B3BE488AF3F2A2E3C6C?sequence=1. 2015.
World Health Organization awareness week 2017 [internet]. [cited 2018 Feb 23]. Available from: http://www.who.int/campaigns/world-antibioticawareness-week/en/.
The Review on Antimicrobial Resistance [internet]. [cited 2020 March 12]. Available from: https://amr-review.org/sites/default/files/160518/Final paper.pdf.
Kosiyaporn H, Chanvatik S, Issaramalai T, Kaewkhankhaeng W, Kulthanmanusorn A, Saengruang N, et al. Surveys of knowledge and awareness of antibiotic use and antimicrobial resistance in general population: A systematic review. PloS one. 2020;15(1):e0227973.
Worldometer. Pakistan Population [Internet]. [cited 2020 March 12]. Available from: https://www.worldometers.info/world-population/pakistan-population/.
World Population Review [Internet].[cited 2020 March 12]. Available from: https://worldpopulationreview.com/world-cities/karachi-population/.
Raosoft sample size calculator [Internet]. [cited 2019 October 10]. Available from: http://www.raosoft.com/samplesize.
Cochran WG. Sampling techniques: John Wiley & Sons. 2007.
Tavakol M, Dennick R. Making sense of Cronbach's alpha. International journal of medical education. 2011;2:53.
Kaliyaperumal K. Guideline for conducting a knowledge, attitude and practice (KAP) study. AECS illumination. 2004;4(1):7-9.
Kaleem R, Rathore K. Trends of Higher Education among Female Students: The Case of University of the Punjab. Governance and Management Review. 2017;2:1.
Batool SQ, Sajid M, Shaheen I. Gender and higher education in Pakistan. International Journal of Gender and Women’s Studies. 2013;1(1):15-28.
Vila J, Pal T. Update on antibacterial resistance in low-income countries: factors favoring the emergence of resistance. The Open Infectious Diseases Journal. 2010;4(1).
Charani E, Cooke J, Holmes A. Antibiotic stewardship programmes—what's missing? Journal of antimicrobial chemotherapy. 2010;65(11):2275-7.
Charani E, Castro-Sánchez E, Holmes A. The role of behavior change in antimicrobial stewardship. Infectious Disease Clinics. 2014;28(2):169-75.
El Zowalaty ME, Belkina T, Bahashwan SA, El Zowalaty AE, Tebbens JD, Abdel-Salam HA, et al. Knowledge, awareness, and attitudes toward antibiotic use and antimicrobial resistance among Saudi population. International journal of clinical pharmacy. 2016;38(5):1261-8.
Minen MT, Duquaine D, Marx MA, Weiss D. A survey of knowledge, attitudes, and beliefs of medical students concerning antimicrobial use and resistance. Microbial Drug Resistance. 2010;16(4):285-9.
Guerra CM, Pereira CAP, Neto ARN, Cardo DM, Correa L. Physicians' perceptions, beliefs, attitudes, and knowledge concerning antimicrobial resistance in a Brazilian teaching hospital. Infection Control & Hospital Epidemiology. 2007;28(12):1411-4.
García C, Llamocca LP, García K, Jiménez A, Samalvides F, Gotuzzo E, et al. Knowledge, attitudes and practice survey about antimicrobial resistance and prescribing among physicians in a hospital setting in Lima, Peru. BMC clinical pharmacology. 2011;11(1):18.
Martinou E, Allan H, Vig S. Personality differences among junior postgraduate trainees in the United Kingdom. Journal of surgical education. 2015;72(1):122-7.
Abdullah MNLY, Mey SC. The Fundamental Lifestyle of a University Community: A Case Study of Higher Education in a Malaysian Institution. Professional Counselor. 2012;2(3):178-91.
Levi-Jakšić M. Proceedings of the XIII International Symposium SymOrg 2012: Innovative Management and Business Performance: University of Belgrade, Faculty of Organizational Sciences; 2012.