Association between Consumption of Social Drug and Coronary Artery Disease among Patients at Kasemrad Prachachuen Hospital, Bangkok

Abstract

Coronary artery disease (CAD) is the cause of one in three deaths among Thais. This unmatchedcase-control study aimed to determine the association between social drug consumption and CAD. The caseswere 140 patients who were undergoing percutaneous coronary intervention and 140 controls selected fromthe OPD and other suitable wards. Data were collected using a structured questionnaire. Chi-square testsand multiple logistic regression were used to identify variables related to CAD.The results showed that 11 variables were significantly associated with CAD: age, education, body massindex (BMI), diabetes, hypertension, hyperlipidemia, a family history of CAD, high fat consumption, lack ofphysical activity, smoking and consumption of energy drinks. Smoking showed a higher risk of CAD (OR = 3.20,95% CI = 1.65-6.20) than alcohol (OR = 0.36, 95% CI = 0.18-0.72) when adjusted for other factors. This studyconcluded that CAD is associated with smoking. We suggest that patients should be provided with knowledgeabout the use of social drugs and the harmful effects of drug-dependent behavior.