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Aim: To study acquired color vision deficiency (ACVD) in Vietnamese patients with primary open angle glaucoma (POAG).
Methods: Cross-sectional descriptive study on 51 eyes of 27 patients with POAG presenting to the Vietnam National Institute of Ophthalmology. Color vision defects were assessed using Farnsworth-Munsell 100 Hue Test. Data were matched to visual field defects on the Humphrey Visual Analyzer (HVFA) and optic nerve analysis on optical coherence tomography (OCT).
Results: 48/51 eyes had color vision defects, with average total error score (TES) of 128.78 ± 117.93. Of these44 of 48 eyes manifested a tritan color vision defect. We found an inverse correlation between TES and mean deviation (MD) on the HVFA (Spearman's Rho Testing, r = -0.238, p < 0.05). The severity of color vision deficiency was correlated to average retinal nerve fiber layer (RNFL) thickness on OCT. There was a high degree of interocular correlation in TES at the FM100Hue; however, asymmetry was noted in patients having different clinical stages of glaucoma between eyes. (Wilcoxon signed-rank test, z = -2.667, p < 0.01). 19.6% of eyes had ACVD without manifest visual field defect on the HVFA and 7.6% eyes had ACVD without decreased RNFL thickness on OCT.
Conclusion: We found a high prevalence of acquired color vision deficiency in our cohort of patients with POAG, suggesting ACVD may be an important finding in POAG.
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