Excimer Laser Phototherapeutic Keratectomy (PTK) in Gelatinous drop-like dystrophy

Main Article Content

Worranart Tattiyakul
Piwat Pipatnoraseth



Gelatinous drop-like corneal dystrophy (GDLD) is a rare corneal dystrophy, characterized by deposition of amyloid in subepithelium and stroma of cornea. Clinical manifestation of GDLD usually present in first 2 decades of life with bilateral multiple white gelatinous subepithelial nodules (mulberry-like configuration) or band keratopathy-like lesion. With time, superficial vascularization has occurred and the lesion progresses to larger and deeper which cause stromal nodules (kumquat-like lesion) and /or stromal opacifications


Download data is not yet available.

Article Details

Case Report


American academy of ophthalmology. BCSC 2015-2016: External disease and Cornea. California : AAO, 2015.

Jayne S. Weiss, Hans Ulrik Møller, Anthony J. Aldave, et al. IC3D Classification of Corneal Dystrophies—Edition 2. Cornea; 2015;34:117–159

Bei Zhang, Yu-Feng Yao. Gelatinous drop-like corneal dystrophy with a novel mutation of TACSTD2 manifested in combination with spheroidal degeneration in a Chinese patient. Molecular Vision 2010; 16:1570-1575

Mina Nakatsukasa, Satoshi Kawasaki, Kenta Yamasaki, et al. Tumor-Associated Calcium Signal Transducer 2 Is Required for the Proper Subcellular Localization of Claudin 1 and 7. The American Journal of Pathology; September 2010, Vol. 177, No. 3

D S Gartry, M G Falcon, R W Cox. Primary gelatinous drop-like keratopathy. British Journal of Ophthalmology; 1989, 73, 661-664

M. Soledad Cortina, Isaac W. Porter, Joel Sugar, Jose de la Cruz. Boston Type I Keratoprosthesis for Visual Rehabilitation in a Patient With Gelatinous Drop-Like Corneal Dystrophy. Cornea; 31, 7, July 2012

Hossein Movahedan, Hamid Reza Anvari-Ardekani, Mohammad Hossien Nowroozzadeh. Limbal Stem Cell Transplantation for Gelatinous Drop-like Corneal Dystrophy. J Ophthalmic Vis Res 2013; 8 (2): 107-112.

T. Yamaguchi, A. Yasuda. Results of Surgical Procedures in Gelatinous Drop-Like Corneal Dystrophy (GDCD) by Scraping With/Without Excimer Laser Phototherapeutic Keratectomy (PTK). Investigative Ophthalmology & Visual Science; May 2003, Vol.44, 4691.

Shimazaki J, Hida T, Inoue M, Saito H, Tsubota K. Long-term follow-up of patients with familial subepithelial amyloidosis of the cornea. Ophthalmology; 1995 Jan; 102(1):139-44.