Retrospective analysis of corneal ectatic disease and associated risk factors at a tertiary hospital in Thailand.

Main Article Content

Monrada Amorntipsakul

Abstract

Background: A study on the prevalence and related factors of corneal ectasia in Thammasat Eye Center. To provide public health information in ways to prevent corneal ectasia and its impact on vision impairment, blindness and other aspects of quality of life. 


Methods: The study is retrospective and descriptive in nature, covering a period from 1 st January 2018 to 31st December 2022  at Thammasat Hospital. 


Results: The data encompasses a total of 68 cases, with 64 (94.11%) cases attributed to keratoconus, 2 (2.94%) cases of pellucid marginal degeneration and 2 (2.94%) cases classified as unspecified corneal ectasia. The study reveals a gender distribution of 33 (48.53%) female patients to 35 (51.47%) male patients. The highest prevalence is found within the age group of 20-29 years (52.94%). Among the 68 cases, 49 individuals (72.05%) have diagnoses of allergic conjunctivitis. 55 individuals (80.88%) have a history of eye rubbing. 23 individuals (33.82%) have documented allergic rhinitis. 18 individuals (26.47%) have a history of wearing contact lenses. Additional aspect reveals that 10 individuals (14.70%) have a history of obstructive sleep apnea. 


Conclusion: The study provides valuable insights into the prevalence and characteristics of corneal ectatic diseases, particularly keratoconus. These insights may contribute to a better understanding of the profile of patients with corneal ectatic diseases in the specified population, facilitating improved diagnosis in terms of more prompt detection and management strategies.


Keywords: Corneal ectasia, Keratoconus

Article Details

Section
Original Study

References

Santodomingo-Rubido J, Carracedo G, Suzaki A, Villa-Collar C, Vincent SJ, Wolffsohn JS. Keratoconus: An updated review. Cont Lens Anterior Eye. 2022 Jun;45(3):101559. doi: 10.1016/j.clae.2021.101559. Epub 2022 Jan 4. PMID: 34991971.

Feder RS, Neems LC. Noninflammatory ectatic disorders. In: Mannis MJ, Holland EJ, eds. Cornea. Vol 1. 4th ed. Elsevier; 2017:820–843.

Pellegrini, M., Bernabei, F., Friehmann, A., Friehmann, A., & Giannaccare, G. (2020). Obstructive Sleep Apnea and Keratoconus: A Systematic Review and Meta-analysis. Optometry and Vision Science (Optom Vis Sci), 97(1), 9-14.

Weed KH, MacEwen CJ, Giles T, Low, J, McGhee CNJ. The Dundee University Scottish Keratoconus study: demographics, corneal signs, associated diseases, and eye rubbing. Eye (Lond). 2008;22(4):534–541.

Belin MW, Duncan JK. Keratoconus: The ABCD Grading System. Klin Monatsbl Augenheilkd. 2016; 233(06):701–707.

Feder RS. Corneal topography. In: Feder RS, ed. The LASIK Handbook: A Case-based Approach. 2nd ed. Wolters Kluwer; 2013:32–39.

Gomes JA, Tan D, Rapuano CJ, et al; Group of Panelists for the Global Delphi Panel of Keratoconus and Ectatic Diseases. Global consensus on keratoconus and ectatic diseases. Cornea. 2015;34(4):359–369.