Endogenous endophthalmitis: A 5-year Retrospective Study at Thammasat Hospital
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Abstract
Purpose: To study clinical features, risk factors, microbiological characteristics, and visual outcomes in patient with endogenous endophthalmitis
Design: Retrospective, observational case series study
Methods: Review of medical records of 16 patients 18 eyes with endogenous endophthalmitis between 2017 -2022 at Thammasat Hospital which had completed in medical record more than 12 months. The initial visual acuity, underlying disease, method of treatment, method of culture etc. had been recorded. From the results of this study, we compared the treatment outcomes between intravenous antibiotics, pars plana vitrectomy, and a combined method. Endophthalmitis from other causes had been ruled out from the study.
Results: 18 eyes of 16 patients who were diagnosed with endogenous endophthalmitis. Mean(±SD) age was 52.75 (±18.58) years. Mean(±SD) onset was 5.43(±7.44) days. Seventy-five percent of patients had udnerlying disease. The most common risk factor was diabetes mellitus and the most common primary site of infection is the urinary tract. Causative organisms were identified in 87.5% of patients. The most common organism was Streptococcus agalactiae (43.75%). The final visual outcomes were no light perception in 29.41%.
Conclusion: Endogenous endophthalmitis is the cause of severe visual loss. Risk factor of endogenous endophthalmitis comes from various causes but diabetes mellitus is still the most common risk factor. Primary vitrectomy with intravitreal antibiotics may be the better option for treatment than intravitreal antibiotics alone.
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