The Study of Factors Predicting Anatomical Success and Visual Outcome Following Macular Hole Surgery in Thammasat University Hospital

Abstract

Purpose: To evaluate Predictors and outcomes for anatomical success in macular hole surgery
Methods: This was a retrospective case-control study of patients diagnosed with macular hole (MH). The preoperative data of the patients including age, gender, laterality, duration of the symptoms, stage and macular hole size were collected. The preoperative
measurement of macular hole size using optical coherence tomography was performed. All patients underwent standardized macular hole surgery, which was pars plana vitrectomy with internal membrane (ILM) peeling, internal gas tamponade, and postoperative face
down positioning, with at least 3 months postoperative follow-up. The primary outcome measurement was anatomical closure of MH, while secondary outcome measurement was postoperative visual acuity improvement.
Results: From the 91 eyes operated, anatomical closure of MH was achieved in 59 eyes (64.8%). The duration of follow-up was at least 3 months. There were statistically significant associations between gender (P=0.025), stage of MH (P<0.001), size of MH (P<0.001), the duration of symptoms (P=0.015), and anatomical closure of MH. Mean BCVA statistically significant improved in success anatomical closure group (-0.39 ± 0.41logMAR ; CI -0.5 to -0.28, P<0.001)
Conclusion: Gender, stage, size, and the duration of symptoms of MH are predictors of successful anatomical closure postoperatively in MH surgery with chance of patients having better visual outcome.