Comparison of Intraocular lens power calculation formulas in primary angle closure glaucoma

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Anuwat Prutthipongsit
Jiranun Research Suptaweeponboon


Objective: To compare the accuracy of the 4 intraocular lens (IOL) power calculation formulas in primary angle closure glaucoma (PACG) eyes. All the formulations in this study are common and widely use; SRK/T, Hoffer Q, Holladay I and Haigis.

Design: Retrospective chart review /retrospective cohort study

Methods: Data collection was performed through the OPD cards of the PACG patients who already pass uneventful cataract surgery with monofocal IOL by Dr. Anuwat Prutthipongsit. All the patients had Pre-operative data collection of Axial length (AL), Anterior Chamber Depth (ACD), Keratometry, and Predicted refractive outcomes using SRK/T, Hoffer Q, Holladay I and Haigis by IOL master (Carl Zeiss). Post-operative data was also collected. Analysis of the accuracy of all formulas was done by comparison of the predicted refractive outcomes and the measured refractive outcomes using the mean error (ME) and mean error square (MES)

Conclusion: The Hoffer Q formula produced the lowest ME (0.009+-0.54 D.), but not the MES (0.303 D.), Whilst the most accuracy formula with the least random error (MES=0.216 D.) is SRK/T with also low ME (0.083+-0.45 D.). The Haigis formula produced the highest MES (0.323 D.) this inaccuracy of the Haigis formula may be caused by biometric data (using ACD). However, There is no statistical significant in different between all this 4 formulas (According to the small sample size). AL is the most weighted variable with significant effect to the predicted refractive error (P=0.029). All four formulas have positive ME representing Hyperopic result than intend.


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