Fluconazole, an effective treatment for Parinaud oculoglandular syndrome associated with Sporotrichosis - case reports and literature review.

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Deivanai Subbiah
Lai Yin Peng
Amir Samsudin


Background: Parinaud oculoglandular syndrome is a unilateral granulomatous, follicular conjunctivitis associated with ipsilateral lymphadenopathy, observed in various bacterial, viral and fungal infections. Fluconazole belongs to the azole class of antifungals and it is used to treat a variety of fungal and yeast infections.


Objective: To report two patients with Parinaud oculoglandular syndrome associated with Sporotrichosis, who were successfully treated with oral Fluconazole.


Methods: Retrospective case reports.



Two healthy female patients presented to our centre with follicular conjunctivitis associated with enlarged ipsilateral pre-auricular and submandibular lymph nodes. Both the patients had history of contact with cats. They were diagnosed with Parinaud oculoglandular syndrome, associated with sporotrichosis and were successfully treated with oral Fluconazole 200mg once daily for 2-3 months.



Fluconazole is an effective alternative to itraconazole in treating Parinaud oculoglandular syndrome associated with sporotrichosis.





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