Variants of ocular meliodosis in Hospital Selayang. A case series

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Jeyarine Royan
Khairy Shamel Sonny Teo
Hanizasurana Hashim


Background: Melioidosis is a multi-system infectious disease which is endemic in Malaysia. Melioidosis causing localized ocular infection has rarely been reported. This study highlights the various ocular manifestations of Melioidosis in patients with positive serology for Burkholderia pseudomallei in Hospital Selayang.

Case Series: There were three patients in this series. All were immunocompetent, with no systemic evidence of infection. One case had unilateral disease; the other two were bilateral, with common presenting symptoms of pain, redness and blurring of vision.

All patients had positive serology for Burkholderia pseudomallei and were treated with intravenous ceftazidime and either oral sulfamethoxazole-trimethoprim (Bactrim) or oral cefuroxime for a minimum of two months.

Conclusions: Melioidosis can manifest as an ocular infection in both the anterior and posterior segments of the eye. The diagnosis is clinical in nature and early empirical therapy should be commenced whilst awaiting confirmatory serology results.

Conflict of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this paper.

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