Effects of Extravasation Prevention Practice Guideline on Extravasation in Patients with Cancer Undergoing Chemotherapy
Keywords:
Extravasation, Extravasation prevention practice guideline, ChemotherapyAbstract
This Post-Test Only Control Group Design study aimed to investigate the effects of Extravasation prevention practice guideline on Extravasation in patients with cancer receiving FOLFOX regimen chemotherapy. A purposive sampling of 70 patients admitted to ward 14 of Chulabhorn Hospital during August 2017 to July 2018 was recruited for this study. 44 patients in comparison group received a standard care, 26 patients in intervention group received evidence-based care. Extravasation was assessed and collected during a cycle of chemotherapy. Data were analyzed using descriptive statistics and Fisher's Exact test. The findings showed that 6 patients (13.64%) in the comparison group had grade 2 Extravasation injuries while there was none in the intervention group. Fisher's Exact test found that there was no difference between the two groups (p = .078). Replication of research and increasing the number of subjects is also suggested.
References
Avdal, E.U. & Aydinoglu, N. (2012 ). Extravasation of
vesicant / non- vesicant drugs and evidence - based
management. International journal of caring
sciences, 5(2), 191-202.
Benna, S.A., Boyle, C.O. & Holley, J. (2013). Extravasation
injuries in adults. ISRN Dermatology., 1-8.
Deery, P. & Laurie, A. (2009). Guidelines for prevention
and management of chemotherapy extravasation.
Surrey, West Sussex and Hampshire cancer
network NHS.
Fidalgo, J.A., Fabregat, L. G., Cervantes, A., Margulies,
A., Vidall, C. & Rolia, F. (2012). Management
of chemotherapy extravasation : ESMO-EONS
clinical practice guidelines. Annals of oncology,
, 68-73.
Gonzalez, T.(2013). Chemotherapy extravasation:
prevention, identification, management, and
documentation. Clinical Journal of Oncology
Nursing, 17, 61-66.
Kreidieh, F.Y., Moukadem, H.A. & Saghir,N.S. (2016).
Overview, prevention and management of
chemotherapy extravasation. World Journal of
Clinical Oncology, 7(1), 87-95.
Molas, F., Ayuso, E. & Oubina, F. (2015). Level of adherence
to an extravasation protocol over 10 years
in a tertiary care hospital. Clinical journal of
oncology nursing, 19, 25-30.
National Cancer Institute. (2015). Chemotherapy.
Retrieved 3 February 2017 from https://www.
cancer.gov/about-cancer/treatment/types/chemotherapy#
Pico, B., Laczo, I., Szatmari, K., Bassam, A., Szabo, Z.,
Ocsai, H. & Csotye, J. (2013). Overview of
extravasation management and possibilities for
risk reduction based on literature data. Journal of
nursing education and practice, 3, 93-105.
Sakaida, E., Sekine, I., Iwasawa, S., Kurimoto, R., Uehara,
T., Ooka, Y., . . . Takiguchi, Y. (2014). Incidence,
risk factors and treatment outcomes of extravasation
of cytotoxic agents in an outpatient
chemotherapy clinic. Japanese Journal of
Clinical Oncology, 44, 168-171.
Sharp, S. (2015). Guideline for management of extravasation
of a cytotoxic agent or a monoclonal
antibody used in treatment of malignant disease.
Guideline for management of extravasation.
Stanley, A. (2011). Guideline for the management of
extravasation. Pan Birmingham cancer network
governance committee chair.
Wengstrom, Y., Foubert, J., Margulies, A., Roe, H. &
Bugeia, S. (2007). Extravasation guidelines 2007.
European Oncology Nursing Society clinical practice
guidelines.
WOSCON Cancer Nursing and Pharmacy Group. (2009).
Chemotherapy extravasation guideline. West of
Scotland Cancer Advisory Network Clinical Leads
Group.