Tuberculin Skin Test Conversion among Health Care Workers in Bamrasnaradura Infectious Diseases Institute, Thailand
Keywords:
Tuberculin skin test, Health Care Workers, Bamrasnaradura Infectious Diseases InstituteAbstract
This study was a routine job to research (Routine to Research: R2R). In Bamrasnaradura InfectiousDisease Institute, Tuberculin skin test (TST) was performed in health care workers (HCW) every year. Thisstudy was a retrospective study aimimg to determine the incidence of the TST conversion by measuringinduration which was 10 mm or more during 2008-2010 .Two hundred and twenty six persons were tested, 37 persons were excluded from the study due to initial TST positive result, the remaining 189 personnel withTST negative were enrolled into the study and subsequent TST were performed in the following year. Theincidence of the TST conversion is 30 % (57 HCW out of 189 HCW). Factors that affected the test resultswere statistically analysed using Relative risk, and multiple logistic regression. It was revealed that TSTconversion was correlated with BCG scar. Another factor that might affect the results of the TST was ahistory of tuberculosis in the family. However, due to small number of enrolled samples statistically significant could not demonstrate (p = 0.06).
Downloads
References
2. World Health Organization (WHO): Global tuberculosis control WHO Report 2011
3. Jarvis WR. Nosocomial transmission of multidrugresistantMycobacterium tuberculosis. Res Microbiol.1993; 144: 117-22
4. Menzies D, Fannin A, Yan L, Fitzgerald M. Tuberculosisamong health care workers. N Engl J Med 1995; 332: 92-8.
5. Edlin BR, Tokars JI, Grieco MH, Crawford JT, Williams J, Sordillo EM, et al. An outbreak ofmultidrugresistant tuberculosis among hospitalized patients with the acquired immunodficiency syndrome.N Engl J Med 1992; 326: 1514-21
6. Zaza S, Blumberg HM, Beck-Sague C,Haas WH,Woodley CL, Pineda M, et al. Nosocomial transmission of Mycobacterium tuberculosis: role of health care workers in outbreak propagation. J Infect Dis 1995; 172: 1542-9
7. Centers for Disease Control and Prevention. Guide235 lines for preventing the transmission of Mycobacterium tuberculosis in health-care facilities, 1994. MMWR Morb Mortal Wkly Rep 1994; 43(RR-13): 1-132
8. Panyananadana V, Kladphuang B, Somsong W,et al.Battle against TB : Natinal tuberculosis programme,Thailand, 1999. Bangkok: Tuberculosis Division, 1999 .
9. World Health Organization. WHO policy on TBinfection control in health-care facilities, congregatesettings and households [Internet]. 2009 [cited 2009 Oct 1]. Available from: http://whqlibdoc.who.int/ publications/2009/9789241598323_eng.pdf
10. Kraut A, Coodin M, Plessis R, McLean D Predictorsof Positive Tuberculin Skin Test (TST) Results after2-Step TST among Health Care Workers in Manitoba, Canada. Clin Infect Dis 2004; 39: 113-8
11. Larsen NM, Biddle CL, Sotir MJ, White N, Parotte P, Blumberg HM. Risk of Tuberculin Skin TestConversion among Health Care Workers: Occupational versus Community Exposure and Infection. Clin Infect Dis 2002; 35: 796-801
12. Kassim s, Zuber P, Wiktor SZ, Diomande FV, Coulibaly IM, Coulibaly D, et al. Tuberculin skin.testing to assess the occupational risk of Mycabacterium tuberculosis infection among health care workers in Abidjan, Cote d' Ivoire. Int J Tuberc Lung Dis(4): 321-326
13. Do AN, Limpakarnjarat K,Uthaivoravit W,Zuber PL,Korattana S, Binkin N,et al. Increase risk ofMycobacterium tuberculosis infection related to the occupational exposures of health care workers inChiang Rai, Thailand. Int J Tuberc Lung Dis 3(5): 377-381
14. M Dyrhol-Riise A, Gran G, Wentzel-Larsen T, Blomberg B, Haanshuus CG, M?rkve O. Diagnosis and follow-up of treatment of latent tuberculosis; the utility of the QuantiFERON-TB Gold In-tube assay in outpatients from a tuberculosis low-endemic country.BMC Infectious Diseases 2010, 10: 57
15. W. Jiamjarasrangsi, N. Hirunsuthikul, P. Kamolratanakul. Tuberculosis among health careworkers at King Chulalongkorn Memorial Hospital,
1988-2002. Int J Tuberc Lung Dis 9 (11): 1253-1258
16. Tan L H, Kamarulzaman A, Liam C K, Lee T C.Tuberculin skin testing among healthcare workers in the University of Malaya Medical Centre, Kuala Lumpur, Malaysia. Infect Control Hosp Epidemiol 2002; 23: 584-590
17. Cuhadaroglu C, Erelel M, Tabak L, Kilicaslan Z. Increased risk of tuberculosis in health care workers: a retrospective survey at a teaching hospital in Istanbul, Turkey. BMC Infect Dis 2002; 2: 14
18. Kanyerere H S, Salaniponi F M. Tuberculosis in health care workers in a central hospital in Malawi.Int J Tuberc Lung Dis 2003; 7: 489-492
19. Borroto S, G?mez D, D?az D, Mart?nez Y, Ferrer AI, Vel?squez Y,et al. Latent tuberculosis infection among health care workers at a general hospital In Santiago de Cuba. Int J Tuberc Lung Dis. 2011; 15(11): 1510-4
20. Paduungchan S, Kajanart S, Kasriatta S, Daremas S, Ten Dam GG. The efectiveness of BCG vaccination of the newborn against childhood tuberculosis in Bangkok. Bull World Health Organ. 1986; 64: 247-58
21. Khawcharoenporn T, Apisarnthanarak A, Thongphubeth K, Yuekyen C, Mundy L M. Tuberculin skin testsamong medical students with prior bacilli Calmette-Gu?rin vaccination in a setting with a high prevalence of tuberculosis. Infect Control Hosp Epidemiol 2009; 30: 705-709
Downloads
Published
How to Cite
Issue
Section
License
Articles published in the Disease Control Journal are considered as academic work, research or analysis of the personal opinion of the authors, not the opinion of the Thailand Department of Disease Control or editorial team. The authors must be responsible for their articles.