TY - JOUR AU - Hai, Le Dinh AU - Chockmangmeepisan, Putita AU - Sakulworakan, Rungnapa AU - Dong, Ha Thanh AU - Kayansamruaj, Pattanapon AU - Rung-ruangkijkrai, Tiladit AU - Pirarat, Nopadon AU - Rodkhum, Channarong PY - 2020/06/12 Y2 - 2024/03/29 TI - Virulence properties and pathogenicity of Flavobacterium columnare in hybrid red tilapia (Oreochromis sp.) JF - The Thai Journal of Veterinary Medicine JA - TJVM VL - 50 IS - 1 SE - Original Articles DO - UR - https://he01.tci-thaijo.org/index.php/tjvm/article/view/243263 SP - 103-108 AB - <p><span class="fontstyle0">Flavobacterium columnare </span><span class="fontstyle2">is the causative organism of columnaris disease in freshwater fish, which may exhibit<br>differences in pathogenicity. The virulence properties and the pathogenicity of </span><span class="fontstyle0">F. columnare </span><span class="fontstyle2">in juvenile hybrid red<br>tilapia were investigated using a collection of </span><span class="fontstyle0">F. columnare </span><span class="fontstyle2">isolates recovered from diseased fish. Ten isolates were<br>selected to perform immersion challenge assay in juvenile tilapia. The pathogenicity was highly diverse. Subsequently,<br>three bacterial isolates exhibited different pathogenicity levels, consisting of high, moderate and low virulence (100%,<br>80% and 0% mortality respectively) and were subjected to virulence properties evaluation e.g. the median lethal dose<br>(LD</span><span class="fontstyle2">50</span><span class="fontstyle2">), bacterial adhesion, capsular production and biofilm formation. Interestingly, the adhesion ability to the gill<br>surface, biofilm formation and the production of capsular polysaccharide are significantly associated with the highly<br>pathogenic traits of </span><span class="fontstyle0">F. columnare</span><span class="fontstyle2">. These findings suggest that efficient columnaris disease control in farmed fish should<br>target these pivotal virulence properties.</span> </p> ER -