TY - JOUR AU - Aba, Patrick Emeka AU - Ihedioha, John Ikechukwu AU - Nwaogu, Innocent Chima PY - 2020/06/12 Y2 - 2024/03/29 TI - Reference values for certain serum biochemical markers of liver damage in apparently healthy Red Sokoto goats JF - The Thai Journal of Veterinary Medicine JA - TJVM VL - 50 IS - 1 SE - Original Articles DO - UR - https://he01.tci-thaijo.org/index.php/tjvm/article/view/243260 SP - 81-88 AB - <p><span class="fontstyle0">The Red Sokoto goat (RSG) is the most preponderant of all the breeds of goats in Nigeria. There is dearth of<br>information regarding the reference values for serum biochemical markers of liver damage in this breed. This study<br>demonstrated the reference values in apparently healthy RSG and in RSG that were truly negative for liver disorders.<br>The study was a cross sectional survey. Research visits were made to Ikpa Market Abattoir, Nsukka, for 12 weeks</span><span class="fontstyle2">.<br></span><span class="fontstyle0">Apparently healthy goats and those truly negative for liver disorders were deliberately selected for the study</span><span class="fontstyle2">. </span><span class="fontstyle0">Blood<br>samples were collected in sample bottles devoid of anticoagulants. The sera harvested were used for determination of<br>aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyl<br>transferase (GGT) activities and levels of albumin and cholesterol. The overall mean ± standard error of mean (SEM)<br>of the parameters assayed in apparently healthy goats were: AST, 59.54 ± 2.43; ALT, 12.72 ± 1.18; ALP, 38.31 ± 6.63;<br>GGT, 20.83 ± 1.56; albumin, 3.31 ± 0.04; cholesterol, 82.76 ± 1.70 while the overall for the goats that were truly negative<br>for liver disorders were: AST, 53.49 ± 2.23; ALT, 10.91 ± 0.62; ALP, 29.88 ± 2.35; GGT, 16.45 ± 0.91; albumin, 3.37 ± 0.04<br>and cholesterol, 81.36 ± 2.33. Serum ALP was significantly higher in the young rather than the adult goats and in the<br>females more than in the males of apparently healthy RSG while AST was significantly higher in the adults of RSG that<br>showed true negative for liver disorders.</span> </p> ER -