@article{Yang_Cheng_Li_Wang_2020, title={Infection of subgroup J avian leukosis induces erythroblasts and lymphoblasts in Chinese local breed chickens}, volume={50}, url={https://he01.tci-thaijo.org/index.php/tjvm/article/view/244091}, abstractNote={<p><span class="fontstyle0">Anaemia, emaciation, increased mortality and decreased egg production were observed in 21 birds in a Chinese<br>local breed flock infected naturally at 240 days old. Macroscopically, the spleen and kidneys were enlarged. There were<br>diffuse, multifocal white foci on the surface of the liver, lungs and ovaries. Histopathological examination<br>demonstrated typical lymphosarcoma cells and erythroblasts in the lungs, spleen, liver, kidneys and ovaries. The<br>results of polymerase chain reaction (PCR) showed that avian leukosis virus subgroup J (ALV-J) was positive in the<br>liver, spleen and ovaries. Immunofluorescence assay results further confirmed the presence of ALV-J antigen in the<br>liver, kidneys and ovaries. Sequence analysis of the specific nucleotides fragments demonstrated that the viruses were<br>closest to the United Kingdom (UK) prototype strain virus HPRS-103 (97.8% to 98.2%). This is the first report of<br>erythroblasts and lymphoblasts caused by ALV-J in Chinese local breed chickens.</span> </p>}, number={2}, journal={The Thai Journal of Veterinary Medicine}, author={Yang, Jie and Cheng, Ziqiang and Li, Chengui and Wang, Guihua}, year={2020}, month={Jun.}, pages={277–281} }