@article{Suriyaphol_Leelakajornkit_Sripodok_Kallayanathum_Komonpunporn_Am-in_Pisamai_Yimpring_2020, title={Testicular gene expression of Anti-Müllerian hormone, Androgen receptor and Inhibin alpha subunit in porcine cryptorchidism}, volume={50}, url={https://he01.tci-thaijo.org/index.php/tjvm/article/view/244077}, abstractNote={<p><span class="fontstyle0">Cryptorchidism, one of the common congenital abnormalities in boars, results in a boar taint in the carcass and<br>economic loss. However, knowledge of gene expression of hormones controlling the testicular descent process, such as<br>anti-Müllerian hormone (</span><span class="fontstyle2">AMH</span><span class="fontstyle0">), androgen receptor (</span><span class="fontstyle2">AR</span><span class="fontstyle0">) and inhibin alpha subunit (</span><span class="fontstyle2">INHA</span><span class="fontstyle0">), in porcine testicular<br>cryptorchidism is still limited. The present study aimed to investigate the gene expression profiles of </span><span class="fontstyle2">AMH</span><span class="fontstyle0">, </span><span class="fontstyle2">AR </span><span class="fontstyle0">and<br></span><span class="fontstyle2">INHA </span><span class="fontstyle0">in undescended testes (UDT) and descended testes (DT) in unilateral cryptorchid pigs of suckling (1</span><span class="fontstyle3"></span><span class="fontstyle4">2 </span><span class="fontstyle0">weeks of<br>age), nursery (6 weeks of age) and growing-finishing pigs (15</span><span class="fontstyle3"></span><span class="fontstyle0">20 weeks of age) and in normal testes (NT) at 1</span><span class="fontstyle3"></span><span class="fontstyle4">2 </span><span class="fontstyle0">weeks<br>of age, using quantitative real-time reverse transcription PCR (qRT-PCR). A significant decrease in expression of </span><span class="fontstyle2">AMH<br></span><span class="fontstyle0">and </span><span class="fontstyle2">AR </span><span class="fontstyle0">genes in the UDT group was observed compared with the DT group at 15</span><span class="fontstyle3"></span><span class="fontstyle0">20 weeks. Within each group, the<br>highest expression of </span><span class="fontstyle2">AMH </span><span class="fontstyle0">was observed at 6 weeks of age, whereas the lowest expression was shown at 15</span><span class="fontstyle3"></span><span class="fontstyle0">20 weeks<br>compared with other ages. For the expression of </span><span class="fontstyle2">AR</span><span class="fontstyle0">, the lowest expression was revealed only in the UDT group at<br>15</span><span class="fontstyle3"></span><span class="fontstyle0">20 weeks compared with other ages. Prominent expression of </span><span class="fontstyle2">AR </span><span class="fontstyle0">and </span><span class="fontstyle2">INHA </span><span class="fontstyle0">was observed in the DT group at 20<br>weeks. In conclusion, this study unveiled the decreased expression of </span><span class="fontstyle2">AMH </span><span class="fontstyle0">and </span><span class="fontstyle2">AR </span><span class="fontstyle0">genes in UDT compared with DT<br>in growing-finishing pigs. Markedly increased expression of </span><span class="fontstyle2">AR </span><span class="fontstyle0">and </span><span class="fontstyle2">INHA </span><span class="fontstyle0">was observed in DT when pigs reached<br>puberty.</span> </p>}, number={2}, journal={The Thai Journal of Veterinary Medicine}, author={Suriyaphol, Gunnaporn and Leelakajornkit, Shanaporn and Sripodok, Wipa and Kallayanathum, Wirakan and Komonpunporn, Arunthip and Am-in, Nutthee and Pisamai, Sirinun and Yimpring, Nathamon}, year={2020}, month={Jun.}, pages={211–217} }