@article{Ting_Ponge_Chou_Wang_Chen_Lee_2020, title={Comparison of plasma-lyte A and trometamol-balanced priming solutions for cardiopulmonary bypass in a swine model: a pilot study}, volume={50}, url={https://he01.tci-thaijo.org/index.php/tjvm/article/view/243255}, abstractNote={<p><span class="fontstyle0">Currently, the optimal priming solution for cardiopulmonary bypass (CPB) remains debatable. However, plasmalyte A solution (PLAS) has been widely used in the United States and is considered to be the standard priming solution<br>worldwide. Therefore, we designed a trometamol-balanced solution (Resculyte® solution, RS) to evaluate the safety<br>and feasibility for its use as a priming solution during CPB compared to PLAS. In total, 8 white pigs that underwent<br>CPB were assigned 1:1 to PLAS and RS groups. Hemodynamic parameters were recorded using an Abbott i-STAT<br>analyzer with CG4+ (for pH, pressure of carbon dioxide, pressure of oxygen , total carbon dioxide, bicarbonate, base<br>excess, oxygen saturation, and lactate), CG6+ (for sodium, potassium, chloride, blood glucose, blood urea nitrogen,<br>hematocrit, and hemoglobin), and cardiac troponin I (cTnI) cartridges during and after CPB. The parameters of<br>chemistries, electrolytes, and blood gas exhibited similar trends and revealed no considerable changes during and after<br>CPB. However, the pH values of the RS group remained stable compared with the PLAS group. Moreover, the cTnI<br>levels of the RS group were lower than those of the PLAS group, particularly on day 2. In conclusion, RS was a safe and<br>feasible priming solution in this pilot study during CPB. Future study will increase the data of swine models with CPB<br>to assess the clinical practice of RS compared to PLAS.</span></p>}, number={1}, journal={The Thai Journal of Veterinary Medicine}, author={Ting, Wen-Ting and Ponge, Lee-Mei and Chou, Heng-Wen and Wang, Chih-Hsien and Chen, Yih-Sharng and Lee, Jih-Jong}, year={2020}, month={Apr.}, pages={33–42} }