Localized histiocytic sarcoma in a captive capybara (Hydrochoerus hydrochaeris)


  • Saralee Srivorakul
  • Kittikorn Boonsri
  • Thewarach Vechmanus
  • Pinich Boonthong
  • M. Gerard O’Sullivan
  • Kidsadagon Pringproa


Capybara, histiocytic sarcoma, Hydrochoerus hydrochaeris


An irregular, subcutaneous mass (2x3x2 cm) located between the first and second digits of the left hindlimb of a nine-year-old, male, captive capybara (Hydrochoerus hydrochaeris) was biopsied. Microscopically, the mass scattered throughout the dermis. The neoplastic cells were arranged in solid-sheet patterns and comprised of pleomorphic histiocytic cells with pleomorphic nuclei and abundant eosinophillic cytoplasm. Mitotic figures were 2-3 cells/HPF. Numerous, multinucleated, giant cells, up to 10 nuclei/cells, were also prominently observed and found scattered throughout the mass. Immunohistochemically, the neoplastic cells were strongly positive for vimentin and ionized calcium-binding adaptor molecule 1 (Iba-1), while immunoreactivity for cytokeratin was negative. Based on histopathological and immunohistochemical characterizations, localized histiocytic sarcoma was diagnosed.


How to Cite

Srivorakul, S., Boonsri, K., Vechmanus, T., Boonthong, P., O’Sullivan, M. G., & Pringproa, K. (2017). Localized histiocytic sarcoma in a captive capybara (Hydrochoerus hydrochaeris). The Thai Journal of Veterinary Medicine, 47(1), 131–135. Retrieved from https://he01.tci-thaijo.org/index.php/tjvm/article/view/82197



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