Field study of seroconversion of three different commercial vaccines of chicken infectious anemia virus in Thailand

Abstract

The aim of this study was to evaluate the effects of different chicken infectious anemia virus (CIAV) vaccine strains in breeders and progeny under field conditions. For this experiment, one commercial poultry company was selected, and independent management for each house was applied to avoid vaccine cross contamination. No natural infection was found before vaccination. BioChek ELISA kits were used, and a minimum of 20 birds per flock were sampled in each sampling time. Three commercial CIAV vaccine strains that are available in Thailand were selected for the study: 26P4 was vaccinated subcutaneously, Cux-1 was vaccinated orally, and Del Ros was vaccinated via wing web. The vaccine strains were administered to different flocks at 8, 8 and 6 weeks of age, respectively, following the manufacturers’ instructions. At 14 weeks of age, average antibody titers against 26P4, Cux-1 and Del Ros were 1,650.78, 3,993.94 and 2,409.89; %coefficients of variance were 60, 19 and 40%; and vaccination indices were 28, 210 and 60, respectively. At 14, 23, 27, 32 and 50 weeks of age, the birds that received Cux-1 revealed significantly higher antibody titers than the birds that received 26P4 at the same age (p <0.05). The birds vaccinated with Cux-1 showed 100% positive serum samples 6 weeks after vaccination. Birds that hatched from the broiler breeders vaccinated with Cux-1 at the ages of 27, 32, 50 and 61 weeks revealed significantly higher antibody titers than those of the birds vaccinated with 26P4 (p <0.05).