THE DETECTION OF EQUINE HERPESVIRUS ANTIGEN IN AN ABORTED FOAL USING IMMUNOHISTOCHEMISTRY : A CASE REPORT

Abstract

Formalin fixed tissues from an aborted foal which had been diagnosed as having Equine
Herpesvirus (EHV) infection, on histopathological criteria, were examined for EHV antigen using immunohistochemistry. EHV antigen was found in the focal necrotic area of the liver, especially in hepatocytes and Kupffer cells. Intranuclear and intracytoplasmic, immuno-positive labelings were also prominent in bronchiolar epithelial cells. The method allowed the visualization of the antigenic site distribution and their subsequent correlation with histopathological changes.