PERACUTE INFECTION OF ACTINOBACILLUS PLEUROPNEUMONIAE SEROTYPE 1 IN GUINEA PIGS

Authors

  • Anongnart Somchit
  • Pornchalit Assavacheep
  • Wantanee Neramitmansook
  • Achariya Sailasuta

Keywords:

Actinobacillus pleuropneumoniae, guinea pigs, peracute infection

Abstract

This experiment was performed to study gross and microscopic lung lesions after endotracheal inoculation with Actinobacillus pleuropneumoniae (A. pleuropneumoniae) serotype 1 in twenty-four guinea pigs. Four-six hours post inoculation, clinical signs of respiratory distress and epistasis were observed. Most of the infected animals
suddenly died during this time. The differences between the pulmonary lesions were evaluated. In this experiment, the lesions of peracute infection by A. pleuropneumoniae were induced within 4-6 hours and the lesions of subacute infection, characterized by fibrinopurulent pleuritis were observed in surviving animals 18-20 hours post
inoculation. The results suggested that guinea pigs could be used as a model for the study the pathogenesis of A. pleuropneumoniae infection in pigs.

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How to Cite

Somchit, A., Assavacheep, P., Neramitmansook, W., & Sailasuta, A. (2015). PERACUTE INFECTION OF ACTINOBACILLUS PLEUROPNEUMONIAE SEROTYPE 1 IN GUINEA PIGS. The Thai Journal of Veterinary Medicine, 34(1), 21–28. Retrieved from https://he01.tci-thaijo.org/index.php/tjvm/article/view/37376

Issue

Vol. 34 No. 1 (2004): March

Section

Original Articles