THE EFFECT OF CYPERMETHRIN ON LAYING CHICKS (GALLUS DOMESTICUS) WHEN USED AT THERAPEUTIC DOSES FOR ECTOPARASITIC TREATMENT, BY MEASURING SERUM CHOLINESTERASE ACTIVITY

Abstract

The effect of cypermethrin at therapeutic doses for ectoparasitic treatment in laying chicks was evaluated by the measurement of serum cholinesterase (ChE) activity. The chicks were divided into 5 groups, 20 in each group. All chicks in groups 2 and 3 were bathed with 0.05 ppm cypermethrin for 2 min, while the chicks in group 4 and 5 were bathed with 200 ppm cypermethrin for 2 min. Group 1 acted as a control group. Serum ChE activity in all the chicks in groups 2 and 4 were measured 24 hr after exposure. ChE activity in the chicks in groups 3 and 5 were measured 96 hr after exposure. A significant reduction of serum ChE activity was founded in group 4 (p<0.05) when compared to the control group. There were no clinical signs in any chicks throughout the experiment. The result suggests that a sublethal effect occurs when cypermethrin, at the dosage of 200 ppm, is used for the
treament of chick ectoparasitic disease.