Core and characteristic oral microorganisms in the giant pandas (Ailuropoda melanoleuca) suggested plenty of antibiotic resistance prevalence: A mini review

Abstract

The giant panda (Ailuropoda melanoleuca) is a world-recognized rare wildlife endemic to China. Oral microorganisms
may cause dental and other systemic diseases. Additionally, antibiotic resistance in this cute mammal may spread
widely to travelers. In this mini review, we illustrated the oral core microorganisms of the giant pandas and their
characteristics, as well as their prevalence of antibiotic resistance genes. Although there is limited availability in panda
sample collection, researchers have made great efforts to find the characteristics of the giant pandas’ oral microbiota,
including Enterococcus faecium, Enterococcus faecalis, and Staphylococci, with antibiotic resistance genes optrA, VanA,
tetC and so on. Our review suggested plenty of antibiotic resistance prevalence in the giant pandas. Therefore, it is
essential to strengthen the monitoring of antibiotic resistance in giant pandas’ oral microorganisms.