Optimal infusion rate of hypertonic saline to encephalic vessel vasodilatation using magnetic resonance imaging in normovolemic dogs

Authors

  • Yoshiki Murakami
  • Kenji TSUKANO
  • Haruyuki HIRATA
  • Hiroshi KOIE
  • Kazuyuki SUZUKI

Keywords:

encephalic circulation, fluid therapy, hypertonic saline, magnetic resonance imaging, superior sagittal sinus

Abstract

This study aimed to investigate, using magnetic resonance imaging, whether continuous hypertonic saline (HSS) infusion induces a superior vasodilating effect on the encephalic vessels compared to bolus infusion in dogs. The relative cross-sectional area of superior sagittal sinus increased to 1.96±0.09 and 1.69±0.31 times of the pre-value in the continuous and bolus groups, respectively, at t=30 min (p<0.001). However, the relative cross-sectional area of superior sagittal sinus was larger in the continuous group than that in the bolus group (p<0.001). The results suggest that continuous infusion of HSS might be superior to bolus infusion in inducing vasodilatation of the encephalic circulation.

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Published

2022-06-01

How to Cite

Murakami, Y. ., TSUKANO, K. ., HIRATA, H. ., KOIE, H. ., & SUZUKI, K. . (2022). Optimal infusion rate of hypertonic saline to encephalic vessel vasodilatation using magnetic resonance imaging in normovolemic dogs. The Thai Journal of Veterinary Medicine, 52(2), 369–372. Retrieved from https://he01.tci-thaijo.org/index.php/tjvm/article/view/257095

Issue

Section

Short Communications