Immunostimulatory effect of disinfectant on bees

  • Tatiana Romanishina
  • Svitlana Guralska
  • Tetiana Kot
  • Svitlana Furman
  • Oleh Pinsky
  • Diana Feshchenko
  • Zhanna Rybachuk
  • Olexiy Tkachenko
  • Olga Zastulka
  • Svitlana Tushak
Keywords: Apis mellifera, Klebsiella Аerogenes, hemolymph, disinfectant, immunostimulant


The article presents a modern interpretation of the immunostimulatory effect of the disinfectant “Biocontact Plus” on the bee organism. The minimum threshold concentrations of the disinfectant with bactericidal effect were determined in vitro. The stimulating effect of 0.15 % of the concentration of active substances of the disinfectant has been confirmed in vivo. The immunostimulatory effect of this concentration on the immune status of bee colonies is interpreted (the number of young and mature immunocytes). The immunomodulatory effect of 0.15 % disinfectant “Biocontact Plus” on bee haemolymph allows for the use of alternative therapies for bacterial diseases of bees in the future.


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How to Cite
Romanishina, T., Guralska, S., Kot, T., Furman, S., Pinsky, O., Feshchenko, D., Rybachuk, Z., Tkachenko, O., Zastulka, O., & Tushak, S. (2021). Immunostimulatory effect of disinfectant on bees. he hai ournal of eterinary edicine, 51(3), 601-604. etrieved from
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