Systemic aspergillosis involving the mediastinum associated with antifungal therapy in a dog

Abstract

A four-year old, intact female Labrador Retriever dog was presented with a history and clinical signs of vomiting, anorexia and mild dyspnea. Further laboratory examination, by specific canine pancreatic lipase (cPL) test kit and abdominal ultrasound, indicated acute pancreatitis. Results from thoracic radiography and computerized tomography scan showed masses in the cranial and middle mediastinal areas. A cytology examination revealed pyogranulomatous inflammation with the presence of fungal hyphae whereas Aspergillus niger was isolated and identified. Systemic aspergillosis was diagnosed. Many antifungal drugs were introduced and the clinical outcomes were discussed with careful consideration.