Case report: Peripheral iridectomy and sclerectomy for uveitic Glaucoma in a labrador retriever

Abstract

A 4-year-old male Labrador retriever dog presented with a history of conjunctivitis OU and mild buphthalmos OS for one week. Ophthalmic examination revealed corneal edema, conjunctivitis, iritis, aqueous flare, posterior synechia, fibrin on the anterior lens capsule, increased intraocular pressure (IOP =30 mmHg OD; IOP = 48 mmHg OS), weak positive menace response, brisk positive dazzle reflex and negative pupillary light reflex OU. The iridocorneal angle could not be visualized due to corneal edema. Physical examination, hematology and blood chemistry results were normal. Both eyes were diagnosed as having glaucoma and uveitis. Topical prednisolone acetate, atropine sulfate, brinzolamide and timolol including oral doxycyclin and prednisolone were prescribed. The IOP readings in the right eye were initially controlled with medication for only 3-4 weeks whereas the IOPs in the left eye were refractory to treatment. Glaucoma in the left eye became chronic while vision remained in the right eye. One-eighth iridectomy at 10-11 o’clock and 2x6 mm sclerectomy at 10-11 o’clock were performed in the right eye to create aqueous humor passage drainage. Cyclocryotherapy was performed in the left eye. Topical prednisolone acetate, brinzolamide and timolol were applied OU. Seven months postoperatively, the IOPs were maintained within normal OU limits at all examinations. Menace response and dazzle reflex were positive in the right eye. An obstacle course was positive when the left eye was covered.