Patients with Melioidotic septic arthritis in Nakhonphanom Hospital
Keywords:
septic arthritis, melioidosisAbstract
Objective: To study the demographic pattern, clinical characteristics, laboratory, treatment, outcome , and length of stay in patients with melioidotic septic arthritis.
Materials and methods: This study was a retrospective study to review patients with melioidotic septic arthritis at Nakhonphanom Hospital between 1 October 2016 and 30 September 2021. The data were analyzed by frequency, percentage, mean , and standard deviation.
Results: A total of 32 patients showed that the male to female ratio was 1.38: 1. The mean age was 56.62+12.72 years. The most of them were farmers 29 cases (90.62%). The most common predisposing condition was diabetic Mellitus 29 cases (90.62%). Duration before reaching hospital was 1-7 days (68.75%), average 8.45+6.24 days. All of them presented with fever, pain ,and swelling (100.00%). The most common site of infection was the knee joint 15 cases (46.87%), followed by the shoulder 6 cases (18.75%), the elbow 5 cases (15.62%), the hip 4 cases (12.80%), the wrist and the ankle was 1 case (3.12%). The diagnosis was made on the basis of the positive culture of burkholderia pseudomallei, Hemocultures were positive in 21 cases (65.62%), and synovial fluids were positive in 17 cases (53.12%), in six patients positive from blood as well as synovial fluid. Treatment included antibiotic therapy with arthrotomy 22 cases (68.75%). The mortality rate was 15.62 percent (5 cases). Length of stay 11.11+5.4 days.
Conclusion: The diagnosis was made on the basis of the positive culture of burkholderia pseudomallei. Treatment as septicemic melioidosis for patients with severe septic arthritis , and risk factors until proven that it is not.
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