TY - JOUR AU - Rahfiludin, Mohammad Zen AU - Pangestuti, Dina R. PY - 2017/04/25 Y2 - 2024/03/29 TI - Phyllanthus Niruri Extract Could Improve Immunoglobulin-M Anti Phenolic Glycolipid-1 Level in Seropositive Contact of Hansen’s Disease Patients JF - Journal of Health Research JA - J Health Res VL - 26 IS - 2 SE - ORIGINAL RESEARCH ARTICLE DO - UR - https://he01.tci-thaijo.org/index.php/jhealthres/article/view/84653 SP - 55-77 AB - <p style="text-align: justify;">Number of Hansen's disease (HD) in Indonesia is classified as number three in the world after India and Brazil. New HD patients tend to increase since there is a possibility that seropositive HD is turning into manifest HD. <em>Phyllanthus niruri  </em>Linn<em>  </em>is an herb that stimulating human immunity to protect from diseases. The aim of this study was to analyze the influence of <em>P niruri</em> extract to the IgM anti PGL - 1 level of seropositive contact of HD patients. Thirty two subjects aged 12-25 year were recruited for this study. The <em>P. niruri </em>group received 50 mg <em>P. niruri </em>extract/day orally for one month. Seropositive HD was determined by examining IgM anti PGL– 1 level. Daily intake was determined by recall method. There was no significant difference daily intake between two groups (<em>P</em> &gt; 0.05).  The IgM anti PGL - 1 level in subject with <em>P. niruri </em>showed lower decrement than the control group, but it was of insignificant difference (<em>P</em>= 0.171). There was no significant change of IgM anti PGL – 1 level between both groups. However, IgM anti PGL – 1 level in the subject in the <em>Phyllantus niruri Linn </em>showed lower decrement.</p> ER -