Relationship between Dyslipidemia and Hypertension: Follow-Up of Medical Record Data in Dyslipidemia Patients

Abstract

Background: Dyslipidemia is associated with atherosclerosis and hypertension. Hyperlipidemia leads to the formation of atherosclerotic plaque and decreases the lumen diameter, whilst increasing the arterial wall resistance and contributing to hypertension. The aim of study was to examine the association between demographic factors, biochemistry factors and hypertension.

Methods: The sample consisted of 203 dyslipidemia patients. Data were collected from the medical records of dyslipidemia patients who visited the Golden Jubilee Medical Center, Mahidol University from 2006-2009. All patients’ follow-ups were based on medical record data through 31 December 2013, looking at survival time of hypertension among dyslipidemia patients.

Results: The results showed that an increase in age corresponded to a fasting blood sugar increase. The body mass index was not related to the total cholesterol level. The increasing body mass index was associated with a HDL-C decrease and a triglyceride and fasting blood sugar increase. The follow-up study was 91.73 months showed that dyslipidemia (at 64%), dyslipidemia and hypertension (at 16.7%), dyslipidemia and impaired fasting blood glucose (at 9.4%), dyslipidemia, hypertension and impaired fasting blood glucose (at 9.9%) all increased. Using a Kaplan Meier analysis of the median survival time of hypertension among dyslipidemia patients (the amount of time after which 50% of the dyslipidemia patients have hypertension), it was found that only the age variable was statistically significant (p=0.001). The median survival time of hypertension among dyslipidemia patients aged ≥ 55 years olds was 64.10 months shorter than in patients aged < 55 years old.

Conclusions: Age was significantly associated with survival time of hypertension among dyslipidemia patients. Policy makers and health promotion campaigns need to address the early screening of dyslipidemia patients, especially the aging population. The general public also needs to be aware of the consequences of the risks after dyslipidemia, such as hypertension and diabetes mellitus.