Detecting Malaria Using SD Bioline Malaria Pf/PAN (HRP2, pLDH)

Abstract

Malaria caused by the Plasmodium species has resulted in significant health problems among most tropical countries. The Plasmodium falciparum is especially a major cause of global morbidity and, in rare cases, mortality, particularly in the infection of children. Rapid detection and prompt treatment is a promising model accepted among malarious countries by using Malaria Rapid Diagnostic Tests (MRDT). We launched Standard Diagnostics (SD) Point of Care Test (POCT) for Malaria detecting either P. falciparum or non-P. falciparum in the malaria control of Thailand.  Two hundred and ninety-nine suspected cases of malaria, who attended three malaria clinics in Kanchanaburi, Ranong and Tak provinces, were recruited. Of those cases, 37.8% (113) were children under 15 years old.  The results showed that the MRDT revealed sensitivity to P. falciparum, non-P. falciparum and specificity at levels of 95.29, 97.57 and 98.21 respectively. Moreover, it represented in similar trend when the children were separated, this test revealed 95.88, 95.00 and 100 sensitivity to P. falciparum and non-P. falciparum specificity respectively. This MRDT showed high diagnostic values and could be used in any malaria endemic areas. In addition, it provides great benefit in detecting malaria in children.