Phototoxic Activity of Selected Thai Rutaceous and Umbelliferous Plant Extracts

Abstract

Phototoxic activity of ethanol extracts from 25 Rutaceous and Umbelliferous species were assessed. Light mediated antimicrobial activities against gram-nagative bacteria, Escherichia coli; gram-positive bacteria, Staphylococcus aureus; gram-positive spores forming bacteria, Bacillus subtilis; yeast Candida albicans and Saccharomyces cerevisiae were conducted. Agar diffusion inhibitions potential with and without UVA irradiation at 360 nm were evaluated. Minimum inhibitory concentrations (MIC) were determined. Thirteen species showed UV-induced inhibitory activity against microorganisms. These were from both families as follow: Aegle marmelos (L.) Corr., Atalantia monophylla DC., Feroniella lucida (Scheff.) Swingle., Hesperethusa crenulata (Roxb.) Roem., Murraya koenigii L., Triphasia trifolia (Burm.t.) P. Wils. in Rutaceous plants and Anethum graveolens L., Angelica dahulica Benth., Apium graveolens, Foeniculum vulgare Mill., Heracleum siamicum Craib, Petroselinum crispum (Miller) A.W. Hill, Pimpinella anisum L. in Umbelliferous plants. Furthermore, these extracts exhibited selectively inhibitory effect against the tested microorganisms. S. aureus strain was mostly selected, followed by B. subtilis, C. albicans and S. cerevisiae respectively whilst E. coli showed negative effect of UV induced inhibitory activity.