Chemical Compostion and Antimicrobial Activity Against Candida Albicans of Essential oil from Leaves of Cinnamomum Porrectum

Authors

  • Chanida Palanuvej Institute of Health Research, Chulalongkorn University, Bangkok, Thailand
  • Pornpen Werawatganone Department of Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
  • Vimolmas Lipipun Department of Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
  • Nijsiri Ruangrungsi (1) Institute of Health Research, Chulalongkorn University, Bangkok, Thailand; (2) Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

Keywords:

Cinnamomum porrectum, essential oil, candida infection

Abstract

Essential oil was distilled from the leaves of Thep-ta-ro, Cinnamomum porrectum (Roxb.) Kosterm., yielded 1.1% of fresh weight. Analysis of essential oil by GC/MS showed that the main component (99.8%) is either iso-safrole or safrole. Further analysis of the oil using proton NMR spectroscopy revealed that the main peak is safrole. The oil was shown to be active against Candida albicans with an MIC 0.063% by volume. Thus, C. porrectum essential oil provided a potential for
treatment of candida infections.

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Published

2019-04-13

How to Cite

Palanuvej, C., Werawatganone, P., Lipipun, V., & Ruangrungsi, N. (2019). Chemical Compostion and Antimicrobial Activity Against Candida Albicans of Essential oil from Leaves of Cinnamomum Porrectum. Journal of Health Research, 20(1), 69–76. Retrieved from https://he01.tci-thaijo.org/index.php/jhealthres/article/view/187317

Issue

Vol. 20 No. 1: March 2006

Section

ORIGINAL RESEARCH ARTICLE