Risk Evaluation of Trichloroethylene Exposure among Workers in Industry

Authors

  • Redeerat Mahaboonpeeti Department of Occupational Health and Safety, Faculty of Public Health, Center of Excellence on Environmental Health, Toxicology and Management of Chemicals (ETM), Mahidol University, Bangkok, Thailand
  • Pornpimol Kongtip Department of Occupational Health and Safety, Faculty of Public Health, Center of Excellence on Environmental Health, Toxicology and Management of Chemicals (ETM), Mahidol University, Bangkok, Thailand
  • Suttinun Chantanakul Department of Occupational Health and Safety, Faculty of Public Health, Center of Excellence on Environmental Health, Toxicology and Management of Chemicals (ETM), Mahidol University, Bangkok, Thailand
  • Vajira Singhakajen Department of Biostatistics, Faculty of Public Health, Mahidol University, Bangkok, Thailand
  • Prapin Tharpoophasiam Department of Social and Environmental Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Keywords:

Trichloroethylene, trichloroacetic acid, risk assessment, Gas Chromatography/Mass Spectrometry

Abstract

The health risks of twenty five workers exposed to trichloroethylene in three factories were studied. Trichloroethylene in the breathing zone of the workers was collected for a full shift following the NIOSH method number 1022 and urine samples were also collected for analysis of trichloroacetic acid metabolite by Gas Chromatography/Mass Spectrometry. The results showed that average concentrations of trichloroethylene in the breathing zone of workers were 15.85 ppm. Thirteen workers (52%) exposed to higher trichloroethylene concentrations than the 10-ppm Threshold Limit Value-Time Weighted Average (TLV-TWA) recommended by the American Conference of Governmental Industrial Hygienists (ACGIH). The average urinary trichloroacetic acid of workers was 90.92 mg/g creatinine (Non-detectable to 349.33 mg/g creatinine). Most workers (88.0 %) had a lower concentration of urinary trichloroacetic acid than the BEI (100 mg/g creatinine) recommended by the ACGIH. Cigarette smoking (p-value = 0.028) had relationship with urinary trichloroacetic acid. There was a fairly high significant correlation between trichloroethylene in the breathing zone of workers and urinary trichloroacetic acid (r = 0.657; p-value < 0.01). This health risk assessment of trichloroethylene exposure found that the workers had excessive cancer risk when using trichloroethylene. The estimated lifetime cancer risk of trichloroethylene exceeded the range of 10-6-10-4 recommended by U.S.EPA.

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Published

2018-11-22

How to Cite

Mahaboonpeeti, R., Kongtip, P., Chantanakul, S., Singhakajen, V., & Tharpoophasiam, P. (2018). Risk Evaluation of Trichloroethylene Exposure among Workers in Industry. Journal of Health Research, 24(3), 95–101. Retrieved from https://he01.tci-thaijo.org/index.php/jhealthres/article/view/156808

Issue

Section

ORIGINAL RESEARCH ARTICLE