Chemical Composition and Antimicrobial Activity of the Essential Oil from Heracleum Siamicum

Authors

  • Tiwatt Kuljanabhagavad (1) Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand; (2) Bioorganic Chemistry Research Laboratories, Faculty of Science and Technology, Suan Dusit Rajabhat University, Bangkok, Thailand
  • Nongluksna Sriubolmas Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
  • Nijsiri Ruangrungsi Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

Keywords:

Heracleum siamicum, antimicrobial activity, chemical composition, hydrodistillation, volatile oil analysis, GC-MS

Abstract

Heracleum siamicum Craib (Apiaceae) is an important herbal spices having a wide applications in flavoring processed foods. The flat-oval shaped fruit of H. siamicum Craib from North Thailand was hydrodistilled and chemical composition of the essential oil was analyzed by GC and GC-MS. The essential oil yield based on dried plant material was 1.25% and twenty-five compounds (corresponding to 97.69% of the total weight) were identified. The main components were: n-octyl acetate (65.30%), o-cymene (10.35%), limonene (7.52%), δ-2-carene (6.87%), cis-thujone (1.92%), isobornyl acetate (0.94%), n-octanol (0.73%), 1,8-cineol (0.62%), n-tridecanol (0.44%), and safrole (0.37%). H. siamicum essential oil demonstrated bactericidal and fungicidal activity against five bacterial strains and two fungal strains, using agar diffusion and minimum inhibitory concentration methods.

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Published

2018-11-22

How to Cite

Kuljanabhagavad, T., Sriubolmas, N., & Ruangrungsi, N. (2018). Chemical Composition and Antimicrobial Activity of the Essential Oil from Heracleum Siamicum. Journal of Health Research, 24(2), 55–60. Retrieved from https://he01.tci-thaijo.org/index.php/jhealthres/article/view/156789

Issue

Section

ORIGINAL RESEARCH ARTICLE