Antimicrobial Efficacy of Caprylyl Glycol and Ethylhexylglycerine in Emulsion

  • Kunlayakorn Lawan Pan Rajdhevee Group Public Company Limited, Pathumthani, Thailand
  • Mayuree Kanlayavattanakul School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand
  • Nattaya Lourith School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand
Keywords: cosmetics, pre servatives, caprylyl glycol, ethylhexylglycerin

Abstract

Antimicrobial efficacies of caprylyl glycol and ethylhexylglycerin in an emulsion were evaluated by USP24-NF19. The minimum concentration of caprylyl glycol and ethylhexylglycerin inhibited Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans within 1 day and Aspergillus niger within 28 days was 0.5% and 1.5%, respectively. The 1:3 mixture ratio of the caprylyl glycol and ethylhexylglycerin was chosen for further steps on inhibitory effect towards those prohibited microbial in cosmetics by evaluation at the concentration of 0.5%, 1.0%, 1.5% and 2.0%, respectively. It was found that the minimum concentration inhibited S. aureus within 3 days, E. coli, P. aeruginosa and C.albicans within 1 day and A. niger within 28 days was 1.0%. This developed preservative system offers multifunctional cosmetic ingredients in addition to their emollient efficacies.

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Published
2018-11-20
How to Cite
Lawan, K., Kanlayavattanakul, M., & Lourith, N. (2018). Antimicrobial Efficacy of Caprylyl Glycol and Ethylhexylglycerine in Emulsion. Journal of Health Research, 23(1), 1-3. Retrieved from https://he01.tci-thaijo.org/index.php/jhealthres/article/view/156308
Section
ORIGINAL RESEARCH ARTICLE