Multiple primary GISTs: Unusual presentation as jejuno-jejunal intussusception

Abstract

Gastrointestinal stromal tumors (GISTs) are rare, occurring in 10 - 15 per million, and 0.2% of all gastrointestinal
tumors, and is generally considered a solitary tumor. This study presented a 57 year-old female with abdominal
pain and intermittent vomiting for 6 months. Acute abdomen series did not show any evidence of a small bowel
obstruction. Esophagogastroduodenoscopy (EGD) suggested partial small bowel obstruction. A contrast enhanced
CT scan (CECT) of the abdomen demonstrated jejuno-jejunal intussusception induced by an intraluminal tumor
and another two mesenteric tumors confirmed by histopathology and immunohistochemistry as GISTs. The
patient had complete resection for treatment. She recovered without complication and remained well. This study
reported a rare case of multiple primary GISTs with unusual presentation as intussusception. CECT is able to detect
tumors, their location, suggest diagnosis, and define complications and metastasis.