Peutz-Jeghers syndrome with disappeared pigmentation on lips after operation: A case report

Abstract

Peutz-Jeghers polyps are hamartomas of the small bowel which occur as part of the Peutz-Jeghers syndrome,
a rare autosomal dominant condition characterized by gastrointestinal polyps and mucocutaneous melanotic
pigmentation. We, hereby, report a case of a young female suffering from this syndrome who presented with
hyperpigmentation of the lips and acute intestinal obstruction due to intussusception. An exploratory laparotomy was performed which revealed jejuno-jejunal and jejuno-ileal intussusceptions for which resection and anastomosis was done. There were multiple intraluminal polyps in the jejunum which upon histopathological examination, showed features of Peutz-Jeghers polyp. But, on postoperative day 11, we found the pigmentation on her lips disappeared, the patient behaved well in the postoperative period.